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Ighv1-16 Gene Detail
Summary
  • Symbol
    Ighv1-16
  • Name
    immunoglobulin heavy variable 1-16
  • Synonyms
    Gm7012
  • Feature Type
    gene segment
  • IDs
    MGI:3647704
    NCBI Gene: 629866
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr12:114629492-114629785 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 62.42 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    98 from dbSNP Build 142
  • Strain Annotations
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3647704
 gene segment Chr12:114629492-114629785 (-)
129S1/SvImJ MGP_129S1SvImJ_G0000080
 gene segment Chr12:117398735-117399028 (-)
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0000157
 gene segment ChrX:117183005-117183298 (-)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0000080
 gene segment Chr12:111115557-111115850 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0000090
 gene segment Chr12:128872751-128873044 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0000099
 gene segment Chr12:115556469-115556762 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0000082
 gene segment Chr12:116841228-116841514 (-)



Homology
more
  • Human Ortholog
    IGHV1-18, immunoglobulin heavy variable 1-18
  • Vertebrate Orthologs
    15
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGHV1-18, immunoglobulin heavy variable 1-18
  • Synonyms
    IGHV118
  • Links
    NCBI Gene ID: 28468
    UniProt: A0A0C4DH31

  • Chr Location
    14q32.33; chr14:106184899-106185394 (-)  GRCh38
  • Human Ortholog
    IGHV1-2, immunoglobulin heavy variable 1-2
  • Synonyms
    IGHV12, V35
  • Links
    NCBI Gene ID: 28474

  • Chr Location
    14q32.33; chr14:105986582-105987083 (-)  GRCh38
  • Human Ortholog
    IGHV1-24, immunoglobulin heavy variable 1-24
  • Synonyms
    IGHV124, VH
  • Links
    NCBI Gene ID: 28467
    UniProt: A0A0C4DH33

  • Chr Location
    14q32.33; chr14:106276546-106277043 (-)  GRCh38
  • Human Ortholog
    IGHV1-3, immunoglobulin heavy variable 1-3
  • Synonyms
    IGHV13, VI-3B
  • Links
    NCBI Gene ID: 28473
    UniProt: A0A0C4DH29

  • Chr Location
    14q32.33; chr14:106005095-106005574 (-)  GRCh38
  • Human Ortholog
    IGHV1-45, immunoglobulin heavy variable 1-45
  • Synonyms
    IGHV145, VH
  • Links
    NCBI Gene ID: 28466
    UniProt: A0A0A0MS14

  • Chr Location
    14q32.33; chr14:106506996-106507491 (-)  GRCh38
  • Human Ortholog
    IGHV1-46, immunoglobulin heavy variable 1-46
  • Synonyms
    IGHV146
  • Links
    NCBI Gene ID: 28465

  • Chr Location
    14q32.33; chr14:106511115-106511856 (-)  GRCh38
  • Human Ortholog
    IGHV1-58, immunoglobulin heavy variable 1-58
  • Synonyms
    IGHV158, VH
  • Links
    NCBI Gene ID: 28464
    UniProt: A0A0C4DH39

  • Chr Location
    14q32.33; chr14:106622357-106622855 (-)  GRCh38
  • Human Ortholog
    IGHV1-69, immunoglobulin heavy variable 1-69
  • Synonyms
    IGHV169, IGHV1E, IGHV1-E
  • Links
    NCBI Gene ID: 28461
    UniProt: P01742

  • Chr Location
    14q32.33; chr14:106714682-106715181 (-)  GRCh38
  • Human Ortholog
    IGHV1-69-2, immunoglobulin heavy variable 1-69-2
  • Synonyms
    IGHV1F, IGHV1-F
  • Links
    NCBI Gene ID: 28458
    UniProt: A0A0G2JMI3

  • Chr Location
    14q32.33; chr14:106737110-106737547 (-)  GRCh38
  • Human Ortholog
    IGHV1-69D, immunoglobulin heavy variable 1-69D
  • Links
    NCBI Gene ID: 102723169
    UniProt: A0A0B4J2H0

  • Chr Location
    14q32.33; chr14:106762092-106762588 (-)  GRCh38
  • Human Ortholog
    IGHV1OR15-1, immunoglobulin heavy variable 1/OR15-1 (non-functional)
  • Synonyms
    IGHV1OR151, IGHV1/OR15-1
  • Links
    NCBI Gene ID: 388077

  • Chr Location
    15q11.2; chr15:22160289-22160930 (-)  GRCh38
  • Human Ortholog
    IGHV1OR15-9, immunoglobulin heavy variable 1/OR15-9 (non-functional)
  • Synonyms
    IGHV1OR159, VSIG7
  • Links
    NCBI Gene ID: 390531

  • Chr Location
    15q11.1; chr15:19964656-19965101 (-)  GRCh38
  • Human Ortholog
    IGHV1OR21-1, immunoglobulin heavy variable 1/OR21-1 (non-functional)
  • Links
    NCBI Gene ID: 390530

  • Chr Location
    21p11.2; chr21:10649390-10649835 (-)  GRCh38
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
  • All Sequences
    13
  • RefSeq
    1
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 629866 NCBI Gene Model | MGI Sequence Detail 294 C57BL/6J ±  kb
polypeptide A0A075B5U1 UniProt | EBI | MGI Sequence Detail 98 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
References
more
  • Summaries
    All 7
    Gene Ontology 1
  • Earliest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory