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Tpbgl Gene Detail
Summary
  • Symbol
    Tpbgl
  • Name
    trophoblast glycoprotein-like
  • Synonyms
    Gm4980
Location &
Maps
more
  • Sequence Map
    Chr7:99273289-99276310 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 54.11 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    145 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3646425
protein coding gene Chr7:99273274-99276310 (-)
129S1/SvImJ ENSMUSG00200043600
protein coding gene Chr7:86096615-86099636 (-)
A/J ENSMUSG00195037602
protein coding gene Chr7:90602005-90605026 (-)
AKR/J ENSMUSG00220045903
protein coding gene Chr7:84018632-84021653 (-)
BALB/cJ ENSMUSG00180030893
protein coding gene Chr7:87275011-87278032 (-)
C3H/HeJ ENSMUSG00175022310
protein coding gene Chr7:87919754-87922770 (-)
C57BL/6NJ ENSMUSG00215027153
protein coding gene Chr7:87119193-87122214 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030031
protein coding gene Chr7:102306207-102309232 (-)
CAST/EiJ ENSTCUG00005030432
protein coding gene Chr7:90512323-90515344 (-)
CBA/J ENSMUSG00210025005
protein coding gene Chr7:87773472-87776488 (-)
DBA/2J ENSMUSG00185056051
protein coding gene Chr7:92094514-92097530 (-)
FVB/NJ ENSMUSG00205036355
protein coding gene Chr7:87773164-87776185 (-)
JF1/MsJ ENSUMUG00000030719
protein coding gene Chr7:97000486-97003502 (-)
LP/J ENSMUSG00230042091
protein coding gene Chr7:98221633-98224654 (-)
NOD/ShiLtJ ENSMUSG00190018503
protein coding gene Chr7:88046361-88049382 (-)
NZO/HlLtJ ENSMUSG00225050738
protein coding gene Chr7:96416471-96419492 (-)
PWK/PhJ ENSLUMG00010049137
protein coding gene Chr7:86234086-86237099 (-)
SPRET/EiJ ENSMSPG00010011792
protein coding gene Chr7:87472295-87475314 (-)
WSB/EiJ ENSIUOG00005010512
protein coding gene Chr7:88391227-88394248 (-)



Homology
more
  • Human Ortholog
    TPBGL, trophoblast glycoprotein like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TPBGL, trophoblast glycoprotein like
  • Links
    NCBI Gene ID: 100507050
    UniProt: P0DKB5

  • Chr Location
    chr11:75240774-75243704 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Tpbgl
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000096606 Ensembl Gene Model | MGI Sequence Detail 3022 C57BL/6J ±  kb
transcript ENSMUST00000178124 Ensembl | MGI Sequence Detail 3022 Not Applicable  
polypeptide ENSMUSP00000137154 Ensembl | MGI Sequence Detail 384 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Gene Ontology 2
    Phenotypes 12
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:123187 Cohen-Barak O, et al., Stem cell transplantation demonstrates that Sox6 represses epsilon y globin expression in definitive erythropoiesis of adult mice. Exp Hematol. 2007 Mar;35(3):358-67

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
09/01/2026
MGI 6.24
The Jackson Laboratory