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Cntnap5a Gene Detail
Summary
  • Symbol
    Cntnap5a
  • Name
    contactin associated protein-like 5A
  • Synonyms
    Caspr5-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:3643623
    NCBI Gene: 636808
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:115612486-116515053 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 51.59 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    29763 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3643623
 protein coding gene Chr1:115612467-116515053 (+)
129S1/SvImJ ENSMUSG00200001505
 protein coding gene Chr1:113116049-114028501 (+)
A/J ENSMUSG00195004491
 protein coding gene Chr1:112404644-113311742 (+)
AKR/J ENSMUSG00220024515
 protein coding gene Chr1:112372524-113273847 (+)
BALB/cJ ENSMUSG00180011823
 protein coding gene Chr1:112687950-113594015 (+)
C3H/HeJ ENSMUSG00175018488
 protein coding gene Chr1:112641090-113542876 (+)
C57BL/6NJ ENSMUSG00215008257
 protein coding gene Chr1:112613160-113515897 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014505
 protein coding gene Chr1:107759017-108651350 (+)
CAST/EiJ ENSTCUG00005005855
 protein coding gene Chr1:111763946-112676187 (+)
CBA/J ENSMUSG00210001064
 protein coding gene Chr1:112529337-113431090 (+)
DBA/2J ENSMUSG00185013624
 protein coding gene Chr1:116918551-117820392 (+)
FVB/NJ ENSMUSG00205011848
 protein coding gene Chr1:111857169-112759276 (+)
JF1/MsJ ENSUMUG00000022971
 protein coding gene Chr1:115564144-116530878 (+)
LP/J ENSMUSG00230006817
 protein coding gene Chr1:116216317-117122258 (+)
NOD/ShiLtJ ENSMUSG00190006025
 protein coding gene Chr1:112529155-113430868 (+)
NZO/HlLtJ ENSMUSG00225002193
 protein coding gene Chr1:120137456-121039587 (+)
PWK/PhJ ENSLUMG00010014326
 protein coding gene Chr1:111826159-112773374 (+)
SPRET/EiJ ENSMSPG00010016424
 protein coding gene Chr1:114091697-115044664 (+)
WSB/EiJ ENSIUOG00005002726
 protein coding gene Chr1:112220322-113115197 (+)



Homology
more
  • Human Ortholog
    CNTNAP5, contactin associated protein family member 5
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CNTNAP5, contactin associated protein family member 5
  • Synonyms
    caspr5
  • Links
    NCBI Gene ID: 129684
    UniProt: Q8WYK1

  • Chr Location
    2q14.3; chr2:124025287-124921219 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    608
  • Tissues
    6
  • cDNA Data
    1
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000070695 Ensembl Gene Model | MGI Sequence Detail 902568 C57BL/6J ±  kb
    transcript ENSMUST00000043725 Ensembl | MGI Sequence Detail 10945 Not Applicable  
    polypeptide ENSMUSP00000035732 Ensembl | MGI Sequence Detail 1304 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000006195 contactin-associated protein like 5-1
      (term hierarchy)
    • InterPro Domains
      IPR001969 Aspartic peptidase, active site
      IPR000421 Coagulation factor 5/8, C-terminal domain
      IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
      IPR000742 EGF-like domain
      IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
      IPR036056 Fibrinogen-like, C-terminal
      IPR008979 Galactose-binding-like domain superfamily
      IPR001791 Laminin G domain
      IPR050372 Neurexin-related cell adhesion and synaptic protein
    • GlyGen
      Q0V8T9 9 sites, 6 N-linked glycans (5 sites), 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 4
      cDNA 1
      Primer pair 1
      Other 2

      Microarray probesets 1
    References
    more
    • Summaries
      All 26
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 10
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory