About   Help   FAQ
Mir486 Gene Detail
Summary
  • Symbol
    Mir486
  • Name
    microRNA 486
  • Synonyms
    mir 486, Mirn486, mmu-mir-486
  • Feature Type
    miRNA gene
  • IDs
    MGI:3619423
    NCBI Gene: 723876
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr8:23632571-23632698 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 11.42 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    26 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3619423
 miRNA gene Chr8:23632571-23632698 (+)
129S1/SvImJ MGP_129S1SvImJ_G0009093
 miRNA gene Chr8:21040287-21040414 (+)
A/J MGP_AJ_G0009076
 miRNA gene Chr8:20341726-20341853 (+)
AKR/J MGP_AKRJ_G0009066
 miRNA gene Chr8:21010205-21010332 (+)
BALB/cJ MGP_BALBcJ_G0009061
 miRNA gene Chr8:20464505-20464632 (+)
C3H/HeJ MGP_C3HHeJ_G0009000
 miRNA gene Chr8:21210489-21210616 (+)
C57BL/6NJ MGP_C57BL6NJ_G0009300
 miRNA gene Chr8:21903344-21903471 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0008833
 miRNA gene Chr8:20643278-20643405 (+)
CBA/J MGP_CBAJ_G0008971
 miRNA gene Chr8:22786419-22786546 (+)
DBA/2J MGP_DBA2J_G0008999
 miRNA gene Chr8:20310158-20310285 (+)
FVB/NJ MGP_FVBNJ_G0009017
 miRNA gene Chr8:20109513-20109640 (+)
LP/J MGP_LPJ_G0009094
 miRNA gene Chr8:21030928-21031055 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0008983
 miRNA gene Chr8:22348808-22348935 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0009270
 miRNA gene Chr8:20916518-20916645 (+)
PWK/PhJ MGP_PWKPhJ_G0008763
 miRNA gene Chr8:19903995-19904122 (+)
SPRET/EiJ MGP_SPRETEiJ_G0008604
 miRNA gene Chr8:20285562-20285689 (+)
WSB/EiJ MGP_WSBEiJ_G0008930
 miRNA gene Chr8:21123678-21123805 (+)



Homology
more
  • Human Ortholog
    MIR486-1, microRNA 486-1
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR486-1, microRNA 486-1
  • Synonyms
    hsa-mir-486, hsa-mir-486-1, MIR486, mir-486-1, MIRN486
  • Links
    NCBI Gene ID: 619554

  • Chr Location
    chr8:41660441-41660508 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    729
  • Tissues
    17
  • Literature Summary
    2
Sequences &
Gene Models
less
  • All Sequences
    22
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 723876 NCBI Gene Model | MGI Sequence Detail 128 C57BL/6J ±  kb
transcript NR_030254 RefSeq | MGI Sequence Detail 128 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 5
    cDNA 1
    Primer pair 2
    Other 2
Other Database
Links
less
miRBase MI0003493
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:345331 Niitsu Y, et al., Increased serum extracellular vesicle miR-144-3p and miR-486a-3p in a mouse model of adipose tissue regeneration promote hepatocyte proliferation by targeting Txnip. PLoS One. 2023;18(5):e0284989
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory