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Ogdhl Gene Detail
Summary
  • Symbol
    Ogdhl
  • Name
    oxoglutarate dehydrogenase-like
  • Feature Type
    protein coding gene
  • IDs
    MGI:3616088
    NCBI Gene: 239017
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:32043976-32070108 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 14, 19.40 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    221 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3616088
protein coding gene Chr14:32043941-32070108 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021143
protein coding gene Chr14:25568937-25595579 (+)
A/J MGP_AJ_G0021091
protein coding gene Chr14:24588190-24614670 (+)
AKR/J MGP_AKRJ_G0021068
protein coding gene Chr14:25735587-25763889 (+)
BALB/cJ MGP_BALBcJ_G0021095
protein coding gene Chr14:24765876-24792678 (+)
C3H/HeJ MGP_C3HHeJ_G0020878
protein coding gene Chr14:25611066-25637434 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021527
protein coding gene Chr14:26590505-26616394 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019090
protein coding gene Chr14:24664554-24689665 (+)
CAST/EiJ MGP_CASTEiJ_G0020403
protein coding gene Chr14:25411596-25437128 (+)
CBA/J MGP_CBAJ_G0020845
protein coding gene Chr14:27569340-27597312 (+)
DBA/2J MGP_DBA2J_G0020967
protein coding gene Chr14:24621278-24648355 (+)
FVB/NJ MGP_FVBNJ_G0020951
protein coding gene Chr14:24583160-24608763 (+)
LP/J MGP_LPJ_G0021036
protein coding gene Chr14:25891045-25917991 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020977
protein coding gene Chr14:26807865-26835812 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021560
protein coding gene Chr14:25515276-25543247 (+)
PWK/PhJ MGP_PWKPhJ_G0020151
protein coding gene Chr14:24101669-24127326 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019975
protein coding gene Chr14:25135407-25162637 (+)
WSB/EiJ MGP_WSBEiJ_G0020458
protein coding gene Chr14:25585235-25612589 (+)



Homology
more
  • Human Ortholog
    OGDHL, oxoglutarate dehydrogenase L
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OGDHL, oxoglutarate dehydrogenase L
  • Synonyms
    YOBELN
  • Links
    NCBI Gene ID: 55753
    neXtProt AC: NX_Q9ULD0
    UniProt: Q9ULD0

  • Chr Location
    10q11.23; chr10:49734641-49762379 (-)  GRCh38

Human Diseases
more
  • Diseases
    1 with human OGDHL associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021913 Ensembl Gene Model | MGI Sequence Detail 26133 C57BL/6J ±  kb
transcript ENSMUST00000022480 Ensembl | MGI Sequence Detail 3449 Not Applicable  
polypeptide ENSMUSP00000022480 Ensembl | MGI Sequence Detail 1029 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • EC
  • InterPro Domains
    IPR011603 2-oxoglutarate dehydrogenase E1 component
    IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain
    IPR001017 Dehydrogenase, E1 component
    IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal
    IPR042179 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily
    IPR029061 Thiamin diphosphate-binding fold
    IPR005475 Transketolase-like, pyrimidine-binding domain
Molecular
Reagents
less
  • All nucleic 11
    cDNA 10
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory