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Mroh8 Gene Detail
Summary
  • Symbol
    Mroh8
  • Name
    maestro heat-like repeat family member 8
  • Synonyms
    4922505G16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3603828
    NCBI Gene: 629499
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:157050470-157121469 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 78.12 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    626 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3603828
 protein coding gene Chr2:157050468-157121612 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026778
 protein coding gene Chr2:162190943-162274819 (-)
A/J MGP_AJ_G0026744
 protein coding gene Chr2:155711993-155784235 (-)
AKR/J MGP_AKRJ_G0026715
 protein coding gene Chr2:160289847-160373498 (-)
BALB/cJ MGP_BALBcJ_G0026753
 protein coding gene Chr2:155999417-156078249 (-)
C3H/HeJ MGP_C3HHeJ_G0026495
 protein coding gene Chr2:160592302-160681551 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027202
 protein coding gene Chr2:166990522-167101937 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024572
 protein coding gene Chr2:149168622-149242528 (-)
CAST/EiJ MGP_CASTEiJ_G0025957
 protein coding gene Chr2:160941279-161022945 (-)
CBA/J MGP_CBAJ_G0026472
 protein coding gene Chr2:173024202-173117350 (-)
DBA/2J MGP_DBA2J_G0026610
 protein coding gene Chr2:154882001-154966533 (-)
FVB/NJ MGP_FVBNJ_G0026577
 protein coding gene Chr2:153281465-153353695 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0026598
 protein coding gene Chr2:176883520-176967489 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027258
 protein coding gene Chr2:160105835-160185347 (-)
PWK/PhJ MGP_PWKPhJ_G0025691
 protein coding gene Chr2:154403158-154481345 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025494
 protein coding gene Chr2:159056967-159138695 (-)
WSB/EiJ MGP_WSBEiJ_G0026027
 protein coding gene Chr2:160997005-161074853 (-)



Homology
more
  • Human Ortholog
    MROH8, maestro heat like repeat family member 8
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MROH8, maestro heat like repeat family member 8
  • Synonyms
    C20orf131, C20orf132
  • Links
    NCBI Gene ID: 140699
    neXtProt AC: NX_Q9H579
    UniProt: Q9H579

  • Chr Location
    20q11.23; chr20:37101167-37179588 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074627 Ensembl Gene Model | MGI Sequence Detail 71000 C57BL/6J ±  kb
transcript ENSMUST00000143663 Ensembl | MGI Sequence Detail 3460 Not Applicable  
polypeptide ENSMUSP00000124362 Ensembl | MGI Sequence Detail 1049 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR011989 Armadillo-like helical
    IPR016024 Armadillo-type fold
    IPR045206 Maestro heat-like repeat-containing protein
    IPR048465 Maestro, HEAT repeats
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 2
References
more
  • Summaries
    All 18
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory