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Degs1l Gene Detail
Summary
  • Symbol
    Degs1l
  • Name
    delta 4-desaturase, sphingolipid 1 like
  • Synonyms
    9130409I23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3588271
    NCBI Gene: 619326
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:180878802-180888232 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 84.52 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    61 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3588271
protein coding gene Chr1:180863166-180888326 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016881
protein coding gene Chr1:187541077-187550498 (+)
A/J MGP_AJ_G0016860
protein coding gene Chr1:179950419-179959824 (+)
AKR/J MGP_AKRJ_G0016826
protein coding gene Chr1:185291382-185300746 (+)
BALB/cJ MGP_BALBcJ_G0016818
protein coding gene Chr1:180585625-180595066 (+)
C3H/HeJ MGP_C3HHeJ_G0016643
protein coding gene Chr1:186078462-186088545 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017281
protein coding gene Chr1:193635024-193644450 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0016224
protein coding gene Chr1:185422775-185432147 (+)
CBA/J MGP_CBAJ_G0016617
protein coding gene Chr1:200764989-200774384 (+)
DBA/2J MGP_DBA2J_G0016723
protein coding gene Chr1:178777746-178787402 (+)
FVB/NJ MGP_FVBNJ_G0016719
protein coding gene Chr1:176876967-176886370 (+)
LP/J MGP_LPJ_G0016797
protein coding gene Chr1:188792783-188802195 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016750
protein coding gene Chr1:207924998-207934467 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017318
protein coding gene Chr1:185072962-185082334 (+)
PWK/PhJ MGP_PWKPhJ_G0016012
protein coding gene Chr1:177897893-177907428 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015788
protein coding gene Chr1:184038656-184047841 (+)
WSB/EiJ MGP_WSBEiJ_G0016287
protein coding gene Chr1:185279745-185289985 (+)



Homology
more
  • Human Ortholog
    DEGS1, delta 4-desaturase, sphingolipid 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DEGS1, delta 4-desaturase, sphingolipid 1
  • Synonyms
    DEGS, DEGS-1, Des-1, DES1, FADS7, HLD18, MIG15, MLD
  • Links
    NCBI Gene ID: 8560
    neXtProt AC: NX_O15121
    UniProt: O15121

  • Chr Location
    1q42.11; chr1:224175756-224193441 (+)  GRCh38

Human Diseases
more
  • Diseases
    1 with human DEGS1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038768 Ensembl Gene Model | MGI Sequence Detail 9431 C57BL/6J ±  kb
transcript ENSMUST00000036819 Ensembl | MGI Sequence Detail 1898 Not Applicable  
polypeptide ENSMUSP00000042889 Ensembl | MGI Sequence Detail 320 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 3
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 18
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory