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Ube2u Gene Detail
Summary
  • Symbol
    Ube2u
  • Name
    ubiquitin-conjugating enzyme E2U (putative)
  • Feature Type
    protein coding gene
  • IDs
    MGI:3588216
    NCBI Gene: 381534
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:100336064-100407342 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 45.72 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    419 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3588216
 protein coding gene Chr4:100336046-100407344 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028487
 protein coding gene Chr4:100751339-100824526 (+)
A/J MGP_AJ_G0028450
 protein coding gene Chr4:97230670-97300739 (+)
AKR/J MGP_AKRJ_G0028397
 protein coding gene Chr4:99565474-99640840 (+)
BALB/cJ MGP_BALBcJ_G0028468
 protein coding gene Chr4:97466501-97540190 (+)
C3H/HeJ MGP_C3HHeJ_G0028181
 protein coding gene Chr4:100404188-100475130 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028907
 protein coding gene Chr4:104572639-104647378 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026199
 protein coding gene Chr4:92570967-92641730 (+)
CAST/EiJ MGP_CASTEiJ_G0027621
 protein coding gene Chr4:98187433-98257974 (+)
CBA/J MGP_CBAJ_G0028150
 protein coding gene Chr4:107847098-107925261 (+)
DBA/2J MGP_DBA2J_G0028300
 protein coding gene Chr4:96935592-97010575 (+)
FVB/NJ MGP_FVBNJ_G0028267
 protein coding gene Chr4:95777386-95846681 (+)
LP/J MGP_LPJ_G0028400
 protein coding gene Chr4:101055036-101125197 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028295
 protein coding gene Chr4:113435221-113507418 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028945
 protein coding gene Chr4:99841906-99917018 (+)
PWK/PhJ MGP_PWKPhJ_G0027346
 protein coding gene Chr4:95105609-95176436 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027168
 protein coding gene Chr4:97296981-97370872 (+)
WSB/EiJ MGP_WSBEiJ_G0027699
 protein coding gene Chr4:99997996-100073636 (+)



Homology
more
  • Human Ortholog
    UBE2U, ubiquitin conjugating enzyme E2 U
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UBE2U, ubiquitin conjugating enzyme E2 U
  • Links
    NCBI Gene ID: 148581
    neXtProt AC: NX_Q5VVX9
    UniProt: Q5VVX9

  • Chr Location
    1p31.3; chr1:64203623-64267368 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotype references
Male mice homozygous for a mutation are viable and show normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    712
  • Tissues
    4
  • cDNA Data
    9
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 381534 NCBI Gene Model | MGI Sequence Detail 71279 C57BL/6J ±  kb
transcript NM_001033773 RefSeq | MGI Sequence Detail 1517 C57BL/6  
polypeptide NP_001028945 RefSeq | MGI Sequence Detail 352 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR000608 Ubiquitin-conjugating enzyme E2
    IPR016135 Ubiquitin-conjugating enzyme/RWD-like
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 13
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory