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Tmem221 Gene Detail
Summary
  • Symbol
    Tmem221
  • Name
    transmembrane protein 221
  • Feature Type
    protein coding gene
  • IDs
    MGI:3525074
    NCBI Gene: 434325
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:72006882-72011515 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 34.43 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    90 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3525074
 protein coding gene Chr8:72006882-72011659 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033753
 protein coding gene Chr8:71967307-71971877 (-)
A/J MGP_AJ_G0033736
 protein coding gene Chr8:69029321-69033889 (-)
AKR/J MGP_AKRJ_G0033662
 protein coding gene Chr8:71064891-71069462 (-)
BALB/cJ MGP_BALBcJ_G0033732
 protein coding gene Chr8:69201247-69205817 (-)
C3H/HeJ MGP_C3HHeJ_G0033442
 protein coding gene Chr8:71647606-71652176 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034250
 protein coding gene Chr8:74701074-74705642 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031192
 protein coding gene Chr8:63664453-63669006 (-)
CAST/EiJ MGP_CASTEiJ_G0032767
 protein coding gene Chr8:71107933-71112499 (-)
CBA/J MGP_CBAJ_G0033420
 protein coding gene Chr8:77354730-77359300 (-)
DBA/2J MGP_DBA2J_G0033574
 protein coding gene Chr8:68758248-68762818 (-)
FVB/NJ MGP_FVBNJ_G0033516
 protein coding gene Chr8:67842794-67847364 (-)
LP/J MGP_LPJ_G0033661
 protein coding gene Chr8:71936978-71941548 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033563
 protein coding gene Chr8:79896224-79900792 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034267
 protein coding gene Chr8:71132038-71136608 (-)
PWK/PhJ MGP_PWKPhJ_G0032474
 protein coding gene Chr8:68041017-68045585 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032311
 protein coding gene Chr8:70072370-70076911 (-)
WSB/EiJ MGP_WSBEiJ_G0032883
 protein coding gene Chr8:71478372-71482944 (-)



Homology
more
  • Human Ortholog
    TMEM221, transmembrane protein 221
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM221, transmembrane protein 221
  • Synonyms
    Jiraiya
  • Links
    NCBI Gene ID: 100130519
    neXtProt AC: NX_A6NGB7
    UniProt: A6NGB7

  • Chr Location
    19p13.11; chr19:17435509-17448668 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Targeted
    4
  • Genomic Mutations
    1 involving Tmem221
  • Find Mice (IMSR)
    16 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000043664 Ensembl Gene Model | MGI Sequence Detail 4634 C57BL/6J ±  kb
transcript ENSMUST00000052072 Ensembl | MGI Sequence Detail 1604 Not Applicable  
polypeptide ENSMUSP00000058317 Ensembl | MGI Sequence Detail 230 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 2
References
more
  • Summaries
    All 22
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory