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Rab44 Gene Detail
Summary
  • Symbol
    Rab44
  • Name
    RAB44, member RAS oncogene family
  • Synonyms
    9830134C10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045302
    NCBI Gene: 442827
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:29333119-29367954 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 15.14 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    359 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3045302
 protein coding gene Chr17:29333102-29367966 (+)
129S1/SvImJ ENSMUSG00200053321
 protein coding gene Chr17:24994098-25022333 (+)
A/J ENSMUSG00195049290
 protein coding gene Chr17:25809701-25837770 (+)
AKR/J ENSMUSG00220053103
 protein coding gene Chr17:24857395-24885463 (+)
BALB/cJ ENSMUSG00180042191
 protein coding gene Chr17:25296583-25324839 (+)
C3H/HeJ ENSMUSG00175050907
 protein coding gene Chr17:24845675-24873745 (+)
C57BL/6NJ ENSMUSG00215050368
 protein coding gene Chr17:24856279-24884441 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021338
 protein coding gene Chr17:24991975-25005301 (+)
CAST/EiJ ENSTCUG00005047475
 protein coding gene Chr17:25581511-25609054 (+)
CBA/J ENSMUSG00210050230
 protein coding gene Chr17:24684107-24712180 (+)
DBA/2J ENSMUSG00185043693
 protein coding gene Chr17:26900206-26928459 (+)
FVB/NJ ENSMUSG00205023151
 protein coding gene Chr17:25168918-25197072 (+)
JF1/MsJ ENSUMUG00000042784
 protein coding gene Chr17:26369391-26397552 (+)
LP/J ENSMUSG00230054973
 protein coding gene Chr17:28419839-28448086 (+)
NOD/ShiLtJ ENSMUSG00190049947
 protein coding gene Chr17:24802931-24830790 (+)
NZO/HlLtJ ENSMUSG00225050236
 protein coding gene Chr17:30397087-30425258 (+)
PWK/PhJ ENSLUMG00010037175
 protein coding gene Chr17:24287322-24315680 (+)
SPRET/EiJ ENSMSPG00010049200
 protein coding gene Chr17:25569880-25603581 (+)
WSB/EiJ ENSIUOG00005049575
 protein coding gene Chr17:25564721-25592890 (+)



Homology
more
  • Human Ortholog
    RAB44, RAB44, member RAS oncogene family
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAB44, RAB44, member RAS oncogene family
  • Synonyms
    dJ431A14.3, RASD3, RASL13
  • Links
    NCBI Gene ID: 401258
    UniProt: Q7Z6P3

  • Chr Location
    6p21.2; chr6:36697826-36733184 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele of both isoforms exhibit impaired granule exocytosis in mast cells and IgE-mediated anaphylaxis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    43
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000064147 Ensembl Gene Model | MGI Sequence Detail 34836 C57BL/6J ±  kb
    transcript ENSMUST00000233717 Ensembl | MGI Sequence Detail 3730 Not Applicable  
    polypeptide ENSMUSP00000156400 Ensembl | MGI Sequence Detail 973 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 7
      Genomic 2
      cDNA 5

      Microarray probesets 3
    References
    more
    • Summaries
      All 37
      Gene Ontology 12
      Phenotypes 8
    • Earliest
      J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
    • Latest
      J:344539 Noguromi M, et al., Rab44 Deficiency Induces Impaired Immune Responses to Nickel Allergy. Int J Mol Sci. 2023 Jan 4;24(2)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory