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Spag6 Gene Detail
Summary
  • Symbol
    Spag6
  • Name
    sperm associated antigen 6
  • Synonyms
    BC061194, Spag6l
  • Feature Type
    protein coding gene
  • IDs
    MGI:3040687
    NCBI Gene: 381350
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:18698808-18754561 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 12.90 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1367 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3040687
 protein coding gene Chr2:18698808-18755224 (+)
129S1/SvImJ ENSMUSG00200040734
 protein coding gene Chr2:15652709-15709123 (+)
A/J ENSMUSG00195016220
 protein coding gene Chr2:15730752-15787422 (+)
AKR/J ENSMUSG00220013535
 protein coding gene Chr2:15723782-15780439 (+)
BALB/cJ ENSMUSG00180036101
 protein coding gene Chr2:15774075-15830497 (+)
C3H/HeJ ENSMUSG00175021476
 protein coding gene Chr2:15735256-15791678 (+)
C57BL/6NJ ENSMUSG00215030245
 protein coding gene Chr2:15824442-15880860 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023208
 protein coding gene Chr2:15136833-15193563 (+)
CAST/EiJ ENSTCUG00005004120
 protein coding gene Chr2:15584395-15645333 (+)
CBA/J ENSMUSG00210003569
 protein coding gene Chr2:15773249-15829667 (+)
DBA/2J ENSMUSG00185038624
 protein coding gene Chr2:15672894-15729536 (+)
FVB/NJ ENSMUSG00205012141
 protein coding gene Chr2:15727602-15784020 (+)
JF1/MsJ ENSUMUG00000003310
 protein coding gene Chr2:15650602-15705448 (+)
LP/J ENSMUSG00230016924
 protein coding gene Chr2:17610986-17667402 (+)
NOD/ShiLtJ ENSMUSG00190014522
 protein coding gene Chr2:15742435-15799087 (+)
NZO/HlLtJ ENSMUSG00225001310
 protein coding gene Chr2:25361554-25417975 (+)
PWK/PhJ ENSLUMG00010032781
 protein coding gene Chr2:15756731-15811566 (+)
SPRET/EiJ ENSMSPG00010014750
 protein coding gene Chr2:16204203-16254125 (+)
WSB/EiJ ENSIUOG00005015293
 protein coding gene Chr2:15818511-15875028 (+)



Homology
more
  • Human Ortholog
    SPAG6, sperm associated antigen 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPAG6, sperm associated antigen 6
  • Synonyms
    CFAP194, CT141, FAP194, pf16, Repro-SA-1
  • Links
    NCBI Gene ID: 9576
    UniProt: O75602

  • Chr Location
    10p12.2; chr10:22345445-22454224 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Homozygous null mice are grossly normal, with normal fertility and sperm parameters, and normal behavior.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    8
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 381350 NCBI Gene Model | MGI Sequence Detail 55754 C57BL/6J ±  kb
transcript NM_001409584 RefSeq | MGI Sequence Detail 2732 C57BL/6  
polypeptide NP_001396513 RefSeq | MGI Sequence Detail 509 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 2
Other
Accession IDs
less
MGI:3757726
References
more
  • Summaries
    All 39
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:388001 Park H, et al., The kinesin-4 protein KIF27 forms a cytoskeletal scaffold at the transition zone to promote motile cilia structural integrity. Proc Natl Acad Sci U S A. 2025 Dec 23;122(51):e2515392122
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory