About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:73288 Sonnenberg-Riethmacher E, et al., Development and degeneration of dorsal root ganglia in the absence of the HMG-domain transcription factor Sox10. Mech Dev. 2001 Dec;109(2):253-65
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3039467
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: anti-Islet-1
Detection system: Secondary antibody coupled to Alexa Fluor
Assay notes: Embryos were fixed in 1% paraformaldehyde.
Results
Specimen 5E: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Note: Double labeled: green - Isl1; red - Sox10 reporter (assay MGI:3039657).
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present Regionally restricted 5E Cells that express Isl1 do not express lacZ and vice versa.

Specimen 5F: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Note: Double labeled: green - Isl1; red - Sox10 reporter (assay MGI:3039657).
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present Regionally restricted 5F Cells that express Isl1 do not express lacZ and vice versa.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory