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Gene Expression Data
Assay Details
Assay
Reference: J:73288 Sonnenberg-Riethmacher E, et al., Development and degeneration of dorsal root ganglia in the absence of the HMG-domain transcription factor Sox10. Mech Dev. 2001 Dec;109(2):253-65
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3039467
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: anti-Islet-1
Detection system: Secondary antibody coupled to Alexa Fluor
Assay notes: Embryos were fixed in 1% paraformaldehyde.
Results
Specimen 5E: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Note: Double labeled: green - Isl1; red - Sox10 reporter (assay MGI:3039657).
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present Regionally restricted 5E Cells that express Isl1 do not express lacZ and vice versa.
Specimen 5F: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Note: Double labeled: green - Isl1; red - Sox10 reporter (assay MGI:3039657).
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present Regionally restricted 5F Cells that express Isl1 do not express lacZ and vice versa.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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