About   Help   FAQ
Mmp27 Gene Detail
Summary
  • Symbol
    Mmp27
  • Name
    matrix metallopeptidase 27
  • Synonyms
    LOC234911
  • Feature Type
    protein coding gene
  • IDs
    MGI:3039232
    NCBI Gene: 234911
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:7571397-7581886 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 9, 2.46 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    49 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3039232
protein coding gene Chr9:7571397-7581886 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034325
protein coding gene Chr9:4433532-4445618 (+)
A/J MGP_AJ_G0034303
protein coding gene Chr9:4538818-4549716 (+)
AKR/J MGP_AKRJ_G0034231
protein coding gene Chr9:4404381-4417983 (+)
BALB/cJ MGP_BALBcJ_G0034297
protein coding gene Chr9:4274772-4286592 (+)
C3H/HeJ MGP_C3HHeJ_G0034008
protein coding gene Chr9:4605994-4616598 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034819
protein coding gene Chr9:4606410-4617508 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031757
protein coding gene Chr9:3796468-3805909 (+)
CAST/EiJ MGP_CASTEiJ_G0033336
protein coding gene Chr9:4621659-4636193 (+)
CBA/J MGP_CBAJ_G0033981
protein coding gene Chr9:4705652-4722243 (+)
DBA/2J MGP_DBA2J_G0034138
protein coding gene Chr9:4416025-4429507 (+)
FVB/NJ MGP_FVBNJ_G0034083
protein coding gene Chr9:4193839-4204211 (+)
LP/J MGP_LPJ_G0034224
protein coding gene Chr9:4484416-4499261 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034127
protein coding gene Chr9:5445526-5467938 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034838
protein coding gene Chr9:4404305-4416844 (+)
PWK/PhJ MGP_PWKPhJ_G0033039
protein coding gene Chr9:4538533-4550537 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032877
protein coding gene Chr9:4649818-4661959 (+)
WSB/EiJ MGP_WSBEiJ_G0033451
protein coding gene Chr9:4416727-4429592 (+)



Homology
more
  • Human Ortholog
    MMP27, matrix metallopeptidase 27
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MMP27, matrix metallopeptidase 27
  • Synonyms
    MMP-27
  • Links
    NCBI Gene ID: 64066
    neXtProt AC: NX_Q9H306
    UniProt: Q9H306

  • Chr Location
    11q22.2; chr11:102691487-102705769 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 234911 NCBI Gene Model | MGI Sequence Detail 10490 C57BL/6J ±  kb
transcript NM_001310717 RefSeq | MGI Sequence Detail 2132 C57BL/6  
polypeptide NP_001297646 RefSeq | MGI Sequence Detail 525 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 1
Other
Accession IDs
less
MGI:2685026
References
more
  • Summaries
    All 24
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:89162 Nuttall RK, et al., Expression analysis of the entire MMP and TIMP gene families during mouse tissue development. FEBS Lett. 2004 Apr 9;563(1-3):129-34
  • Latest
    J:213098 Tocchi A, et al., Functional interactions between matrix metalloproteinases and glycosaminoglycans. FEBS J. 2013 May;280(10):2332-41

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory