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Ugt1a5 Gene Detail
Summary
  • Symbol
    Ugt1a5
  • Name
    UDP glucuronosyltransferase 1 family, polypeptide A5
  • Feature Type
    protein coding gene
  • IDs
    MGI:3032634
    NCBI Gene: 394433
  • Member of
    Ugt1 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:88093734-88146719 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 44.53 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    393 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3032634
 protein coding gene Chr1:88093734-88147724 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016278
 protein coding gene Chr1:89565297-89628377 (+)
A/J MGP_AJ_G0016260
 protein coding gene Chr1:86278049-86334105 (+)
AKR/J MGP_AKRJ_G0016221
 protein coding gene Chr1:88790867-88898479 (+)
BALB/cJ MGP_BALBcJ_G0016217
 protein coding gene Chr1:86398138-86472410 (+)
C3H/HeJ MGP_C3HHeJ_G0016045
 protein coding gene Chr1:89061839-89122337 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016675
 protein coding gene Chr1:92929800-92996654 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014393
 protein coding gene Chr1:80661947-80707867 (+)
CAST/EiJ MGP_CASTEiJ_G0015631
 protein coding gene Chr1:88282670-88339172 (+)
CBA/J MGP_CBAJ_G0016021
 protein coding gene Chr1:95934170-95995691 (+)
DBA/2J MGP_DBA2J_G0016124
 protein coding gene Chr1:85511534-85575533 (+)
FVB/NJ MGP_FVBNJ_G0016123
 protein coding gene Chr1:84607050-84658645 (+)
LP/J MGP_LPJ_G0016194
 protein coding gene Chr1:90645770-90703609 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016148
 protein coding gene Chr1:99169217-99344396 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016716
 protein coding gene Chr1:88890003-88953948 (+)
PWK/PhJ MGP_PWKPhJ_G0015415
 protein coding gene Chr1:84869563-84935762 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015197
 protein coding gene Chr1:87823048-87876017 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    UGT1A4, UDP glucuronosyltransferase family 1 member A4
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UGT1A4, UDP glucuronosyltransferase family 1 member A4
  • Synonyms
    GNT1, hUG-BR1, HUG-BR2, UDPGT, UDPGT 1-4, UGT1, UGT1-01, UGT1-04, UGT1.1, UGT1.4, UGT1A, UGT-1A, UGT1A1, UGT1A4S, UGT1D, UGT-1D
  • Links
    NCBI Gene ID: 54657
    neXtProt AC: NX_P22310
    UniProt: P22310

  • Chr Location
    2q37.1; chr2:233718736-233773300 (+)  GRCh38
  • Human Ortholog
    UGT1A5, UDP glucuronosyltransferase family 1 member A5
  • Synonyms
    UDPGT, UDPGT 1-5, UGT1E
  • Links
    NCBI Gene ID: 54579
    neXtProt AC: NX_P35504
    UniProt: P35504

  • Chr Location
    2q37.1; chr2:233712907-233773300 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Ugt1a5
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    11 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    5
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000089943 Ensembl Gene Model | MGI Sequence Detail 52986 C57BL/6J ±  kb
transcript ENSMUST00000097659 Ensembl | MGI Sequence Detail 2203 Not Applicable  
polypeptide ENSMUSP00000095263 Ensembl | MGI Sequence Detail 529 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • EC
    2.4.1.17
  • InterPro Domains
    IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase
    IPR035595 UDP-glycosyltransferase family, conserved site
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5
References
more
  • Summaries
    All 17
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory