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Or55b4 Gene Detail
Summary
  • Symbol
    Or55b4
  • Name
    olfactory receptor family 55 subfamily B member 4
  • Synonyms
    GA_x6K02T2PBJ9-5206624-5205620, MOR42-3, Olfr544
  • Feature Type
    protein coding gene
  • IDs
    MGI:3030378
    NCBI Gene: 257926
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr7:102133321-102137514 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 54.73 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    146 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3030378
 protein coding gene Chr7:102131238-102137520 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032611
 protein coding gene Chr7:105543944-105548353 (-)
A/J MGP_AJ_G0032586
 protein coding gene Chr7:102841522-102845732 (-)
AKR/J MGP_AKRJ_G0032522
 protein coding gene Chr7:105304096-105311423 (-)
BALB/cJ MGP_BALBcJ_G0032597
 protein coding gene Chr7:102543356-102547811 (-)
C3H/HeJ MGP_C3HHeJ_G0032311
 protein coding gene Chr7:105701833-105707135 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033094
 protein coding gene Chr7:109503330-109509309 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030089
 protein coding gene Chr7:105200891-105201997 (-)
CAST/EiJ MGP_CASTEiJ_G0031637
 protein coding gene Chr7:97262805-97265111 (-)
CBA/J MGP_CBAJ_G0032277
 protein coding gene Chr7:113349438-113353834 (-)
DBA/2J MGP_DBA2J_G0032429
 protein coding gene Chr7:101165432-101169638 (-)
FVB/NJ MGP_FVBNJ_G0032385
 protein coding gene Chr7:100948341-100952819 (-)
LP/J MGP_LPJ_G0032518
 protein coding gene Chr7:106855269-106859849 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032419
 protein coding gene Chr7:114596587-114600917 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033116
 protein coding gene Chr7:104597008-104600304 (-)
PWK/PhJ MGP_PWKPhJ_G0031355
 protein coding gene Chr7:94299515-94301698 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0031754
 protein coding gene Chr7:105264215-105272240 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele show abrogated responses to azelaic acid when on a high fat diet.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    6
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    3
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 257926 NCBI Gene Model | MGI Sequence Detail 4194 C57BL/6J ±  kb
transcript NM_020289 RefSeq | MGI Sequence Detail 1181 C57BL/6  
polypeptide NP_064685 RefSeq | MGI Sequence Detail 334 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • InterPro Domains
    IPR017452 GPCR, rhodopsin-like, 7TM
    IPR000276 G protein-coupled receptor, rhodopsin-like
    IPR000725 Olfactory receptor
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 12
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:341885 Thach TT, et al., Azelaic Acid Induces Mitochondrial Biogenesis in Skeletal Muscle by Activation of Olfactory Receptor 544. Front Physiol. 2020;11:329
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory