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Flrt1 Gene Detail
Summary
  • Symbol
    Flrt1
  • Name
    fibronectin leucine rich transmembrane protein 1
  • Synonyms
    D630040I23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3026647
    NCBI Gene: 396184
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:7069366-7083094 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 5.20 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    366 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3026647
 protein coding gene Chr19:7064829-7143548 (-)
129S1/SvImJ ENSMUSG00200051562
 protein coding gene Chr19:3794895-3808623 (-)
A/J ENSMUSG00195049591
 protein coding gene Chr19:4196801-4210528 (-)
AKR/J ENSMUSG00220037659
 protein coding gene Chr19:3966225-3979954 (-)
BALB/cJ ENSMUSG00180046702
 protein coding gene Chr19:4560367-4574097 (-)
C3H/HeJ ENSMUSG00175011716
 protein coding gene Chr19:3816821-3830549 (-)
C57BL/6NJ ENSMUSG00215046483
 protein coding gene Chr19:4035330-4049060 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022631
 protein coding gene Chr19:3761716-3775789 (-)
CAST/EiJ ENSTCUG00005034732
 protein coding gene Chr19:3937274-3951022 (-)
CBA/J ENSMUSG00210049933
 protein coding gene Chr19:3820223-3833934 (-)
DBA/2J ENSMUSG00185048487
 protein coding gene Chr19:4196698-4210409 (-)
FVB/NJ ENSMUSG00205049474
 protein coding gene Chr19:4194377-4208097 (-)
JF1/MsJ ENSUMUG00000046409
 protein coding gene Chr19:4156083-4169851 (-)
LP/J ENSMUSG00230053688
 protein coding gene Chr19:5121630-5135358 (-)
NOD/ShiLtJ ENSMUSG00190046598
 protein coding gene Chr19:3728088-3741816 (-)
NZO/HlLtJ ENSMUSG00225026766
 protein coding gene Chr19:8830442-8844170 (-)
PWK/PhJ ENSLUMG00010006314
 protein coding gene Chr19:3920183-3933950 (-)
SPRET/EiJ ENSMSPG00010034604
 protein coding gene Chr19:3912458-3926166 (-)
WSB/EiJ ENSIUOG00005043286
 protein coding gene Chr19:3834397-3848125 (-)



Homology
more
  • Human Ortholog
    FLRT1, fibronectin leucine rich transmembrane protein 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FLRT1, fibronectin leucine rich transmembrane protein 1
  • Synonyms
    SPG68
  • Links
    NCBI Gene ID: 23769
    UniProt: Q9NZU1

  • Chr Location
    11q13.1; chr11:64035931-64119173 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
No notable phenotype was detected in a high-throughput screen of homozygous mice.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    694
  • Tissues
    41
  • cDNA Data
    10
  • Literature Summary
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047787 Ensembl Gene Model | MGI Sequence Detail 13729 C57BL/6J ±  kb
transcript ENSMUST00000113383 Ensembl | MGI Sequence Detail 5872 Not Applicable  
polypeptide ENSMUSP00000109010 Ensembl | MGI Sequence Detail 674 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    Genomic 1
    cDNA 10
    Primer pair 1
    Other 1
    Antibodies 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:2147754
References
more
  • Summaries
    All 46
    Developmental Gene Expression 9
    Gene Ontology 7
    Phenotypes 11
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:371488 Chun SH, et al., Cortex folding by combined progenitor expansion and adhesion-controlled neuronal migration. Nat Commun. 2025 Aug 28;16(1):8048
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory