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Cdhr2 Gene Detail
Summary
  • Symbol
    Cdhr2
  • Name
    cadherin-related family member 2
  • Synonyms
    LOC268663, Pcdh24
  • Feature Type
    protein coding gene
  • IDs
    MGI:2687323
    NCBI Gene: 268663
  • Alliance
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:54849276-54884475 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 13, 29.03 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    945 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2687323
protein coding gene Chr13:54849274-54884475 (+)
129S1/SvImJ ENSMUSG00200016111
protein coding gene Chr13:51721702-51756902 (+)
A/J ENSMUSG00195042312
protein coding gene Chr13:51188488-51223712 (+)
AKR/J ENSMUSG00220036265
protein coding gene Chr13:50733134-50768343 (+)
BALB/cJ ENSMUSG00180014915
protein coding gene Chr13:51439765-51474984 (+)
C3H/HeJ ENSMUSG00175034864
protein coding gene Chr13:51226243-51261463 (+)
C57BL/6NJ ENSMUSG00215035092
protein coding gene Chr13:51250739-51285944 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018543
protein coding gene Chr13:50124568-50159079 (+)
CAST/EiJ ENSTCUG00005034660
protein coding gene Chr13:51650522-51685160 (+)
CBA/J ENSMUSG00210036032
protein coding gene Chr13:51431058-51466283 (+)
DBA/2J ENSMUSG00185016711
protein coding gene Chr13:52273012-52308216 (+)
FVB/NJ ENSMUSG00205041338
protein coding gene Chr13:51079842-51115044 (+)
JF1/MsJ ENSUMUG00000013497
protein coding gene Chr13:51675558-51710147 (+)
LP/J ENSMUSG00230031079
protein coding gene Chr13:61617566-61652781 (+)
NOD/ShiLtJ ENSMUSG00190027809
protein coding gene Chr13:51320060-51355264 (+)
NZO/HlLtJ ENSMUSG00225032783
protein coding gene Chr13:55344802-55380003 (+)
PWK/PhJ ENSLUMG00010020079
protein coding gene Chr13:50542683-50577739 (+)
SPRET/EiJ ENSMSPG00010032635
protein coding gene Chr13:50967509-51002475 (+)
WSB/EiJ ENSIUOG00005023453
protein coding gene Chr13:50747073-50782291 (+)



Homology
more
  • Human Ortholog
    CDHR2, cadherin related family member 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDHR2, cadherin related family member 2
  • Synonyms
    PCDH24, PCLCK, PCLKC
  • Links
    NCBI Gene ID: 54825
    UniProt: Q9BYE9

  • Chr Location
    5q35.2; chr5:176542511-176596284 (+)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 268663 NCBI Gene Model | MGI Sequence Detail 35200 C57BL/6J ±  kb
    transcript NM_001033364 RefSeq | MGI Sequence Detail 4131 C57BL/6  
    polypeptide E9Q7P9 UniProt | EBI | MGI Sequence Detail 1308 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 20
      cDNA 20

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2685470
    References
    more
    • Summaries
      All 35
      Diseases 1
      Gene Ontology 7
      Phenotypes 9
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:360372 Cencer CS, et al., Loss of intermicrovillar adhesion factor CDHR2 impairs basolateral junctional complexes in transporting epithelia. Mol Biol Cell. 2024 Nov 1;35(11):br21

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    09/08/2026
    MGI 6.24
    The Jackson Laboratory