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Dcdc2b Gene Detail
Summary
  • Symbol
    Dcdc2b
  • Name
    doublecortin domain containing 2b
  • Synonyms
    Gm12964, LOC384062
  • Feature Type
    protein coding gene
  • IDs
    MGI:2686212
    NCBI Gene: 100504491
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:129502124-129508050 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 63.26 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    136 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2686212
 protein coding gene Chr4:129501723-129508270 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028832
 protein coding gene Chr4:131546294-131552205 (-)
A/J MGP_AJ_G0028791
 protein coding gene Chr4:126285755-126291659 (-)
AKR/J MGP_AKRJ_G0028744
 protein coding gene Chr4:129808876-129814780 (-)
BALB/cJ MGP_BALBcJ_G0028814
 protein coding gene Chr4:126893349-126899253 (-)
C3H/HeJ MGP_C3HHeJ_G0028528
 protein coding gene Chr4:129862173-129868077 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029256
 protein coding gene Chr4:136488913-136494839 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026528
 protein coding gene Chr4:119415864-119421549 (-)
CAST/EiJ MGP_CASTEiJ_G0027960
 protein coding gene Chr4:128051474-128057435 (-)
CBA/J MGP_CBAJ_G0028494
 protein coding gene Chr4:139886113-139892017 (-)
DBA/2J MGP_DBA2J_G0028643
 protein coding gene Chr4:126722016-126727917 (-)
FVB/NJ MGP_FVBNJ_G0028610
 protein coding gene Chr4:125478133-125484263 (-)
LP/J MGP_LPJ_G0028744
 protein coding gene Chr4:131827084-131832995 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028636
 protein coding gene Chr4:144692324-144698231 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029294
 protein coding gene Chr4:130178328-130184232 (-)
PWK/PhJ MGP_PWKPhJ_G0027682
 protein coding gene Chr4:123321868-123328113 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027508
 protein coding gene Chr4:126045985-126051907 (-)
WSB/EiJ MGP_WSBEiJ_G0028041
 protein coding gene Chr4:130305454-130311365 (-)



Homology
more
  • Human Ortholog
    DCDC2B, doublecortin domain containing 2B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DCDC2B, doublecortin domain containing 2B
  • Links
    NCBI Gene ID: 149069
    neXtProt AC: NX_A2VCK2
    UniProt: A2VCK2

  • Chr Location
    1p35.2; chr1:32209089-32216192 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    3
  • cDNA Data
    2
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000078552 Ensembl Gene Model | MGI Sequence Detail 5927 C57BL/6J ±  kb
transcript ENSMUST00000106037 Ensembl | MGI Sequence Detail 1023 Not Applicable  
polypeptide ENSMUSP00000101653 Ensembl | MGI Sequence Detail 340 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 2
    Other 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:3702638
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 14
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:274872 Ingham NJ, et al., Mouse screen reveals multiple new genes underlying mouse and human hearing loss. PLoS Biol. 2019 Apr;17(4):e3000194
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory