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Plpp4 Gene Detail
Summary
  • Symbol
    Plpp4
  • Name
    phospholipid phosphatase 4
  • Synonyms
    C030048B12Rik, LOC381925, Ppapdc1a
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685936
    NCBI Gene: 381925
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:128858755-128993136 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 71.63 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1490 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685936
protein coding gene Chr7:128858114-128993138 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033088
protein coding gene Chr7:133718990-133861829 (+)
A/J MGP_AJ_G0033070
protein coding gene Chr7:130102896-130237916 (+)
AKR/J MGP_AKRJ_G0033002
protein coding gene Chr7:133545577-133684709 (+)
BALB/cJ MGP_BALBcJ_G0033071
protein coding gene Chr7:129769600-129904407 (+)
C3H/HeJ MGP_C3HHeJ_G0032785
protein coding gene Chr7:133426852-133564407 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033581
protein coding gene Chr7:138899796-139050959 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030553
protein coding gene Chr7:131277760-131414828 (+)
CAST/EiJ MGP_CASTEiJ_G0032115
protein coding gene Chr7:125223283-125365271 (+)
CBA/J MGP_CBAJ_G0032758
protein coding gene Chr7:143665014-143806919 (+)
DBA/2J MGP_DBA2J_G0032910
protein coding gene Chr7:128096019-128230462 (+)
FVB/NJ MGP_FVBNJ_G0032863
protein coding gene Chr7:127962068-128096516 (+)
LP/J MGP_LPJ_G0033004
protein coding gene Chr7:135189605-135331567 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032895
protein coding gene Chr7:144680984-144840351 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033600
protein coding gene Chr7:132480916-132623391 (+)
PWK/PhJ MGP_PWKPhJ_G0031821
protein coding gene Chr7:121121219-121261893 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031667
protein coding gene Chr7:119307979-119454073 (+)
WSB/EiJ MGP_WSBEiJ_G0032226
protein coding gene Chr7:133477341-133620266 (+)



Homology
more
  • Human Ortholog
    PLPP4, phospholipid phosphatase 4
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PLPP4, phospholipid phosphatase 4
  • Synonyms
    DPPL2, PPAPDC1, PPAPDC1A
  • Links
    NCBI Gene ID: 196051
    neXtProt AC: NX_Q5VZY2
    UniProt: Q5VZY2

  • Chr Location
    10q26.12; chr10:120456954-120592065 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000070366 Ensembl Gene Model | MGI Sequence Detail 134382 C57BL/6J ±  kb
transcript ENSMUST00000094018 Ensembl | MGI Sequence Detail 1256 Not Applicable  
polypeptide ENSMUSP00000091557 Ensembl | MGI Sequence Detail 271 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 3
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 22
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 2
  • Earliest
    J:244597 Cui W, et al., Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos. Sci Rep. 2016 Nov 21;6:37396
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory