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4930590J08Rik Gene Detail
Summary
  • Symbol
    4930590J08Rik
  • Name
    RIKEN cDNA 4930590J08 gene
  • Synonyms
    LOC381798
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685917
    NCBI Gene: 381798
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:91879790-91927706 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 40.94 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    222 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685917
 protein coding gene Chr6:91877732-91928717 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031053
 protein coding gene Chr6:93527877-93577371 (+)
A/J MGP_AJ_G0031022
 protein coding gene Chr6:89962241-90010943 (+)
AKR/J MGP_AKRJ_G0030953
 protein coding gene Chr6:92450182-92502284 (+)
BALB/cJ MGP_BALBcJ_G0031033
 protein coding gene Chr6:89926716-89975442 (+)
C3H/HeJ MGP_C3HHeJ_G0030675
 protein coding gene Chr6:91925011-91974834 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031492
 protein coding gene Chr6:95944516-95992026 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028659
 protein coding gene Chr6:87945508-87996831 (+)
CAST/EiJ MGP_CASTEiJ_G0030140
 protein coding gene Chr6:92580783-92630604 (+)
CBA/J MGP_CBAJ_G0030719
 protein coding gene Chr6:99519316-99569524 (+)
DBA/2J MGP_DBA2J_G0030872
 protein coding gene Chr6:89140471-89188893 (+)
FVB/NJ MGP_FVBNJ_G0030826
 protein coding gene Chr6:88356336-88404627 (+)
LP/J MGP_LPJ_G0030952
 protein coding gene Chr6:93483607-93532402 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030860
 protein coding gene Chr6:103562383-103612382 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031519
 protein coding gene Chr6:92300641-92349449 (+)
PWK/PhJ MGP_PWKPhJ_G0029856
 protein coding gene Chr6:88099252-88148523 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029685
 protein coding gene Chr6:91210118-91258783 (+)
WSB/EiJ MGP_WSBEiJ_G0030224
 protein coding gene Chr6:92776559-92827177 (+)



Homology
more
  • Human Ortholog
    C3orf20, chromosome 3 open reading frame 20
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    C3orf20, chromosome 3 open reading frame 20
  • Links
    NCBI Gene ID: 84077
    neXtProt AC: NX_Q8ND61
    UniProt: Q8ND61

  • Chr Location
    3p25.1; chr3:14675141-14773036 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    22 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit reduced male fertility associated with oligozoospermia, impaired acrosome reaction, decreased progressive motility, impaired in vivo fertilization, weak sperm-egg interactions, and defects in sperm energy metabolism.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000034063 Ensembl Gene Model | MGI Sequence Detail 47917 C57BL/6J ±  kb
    transcript ENSMUST00000205686 Ensembl | MGI Sequence Detail 3395 Not Applicable  
    polypeptide ENSMUSP00000146101 Ensembl | MGI Sequence Detail 933 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 1
    References
    more
    • Summaries
      All 27
      Gene Ontology 3
      Phenotypes 9
    • Earliest
      J:87486 Akeson EC, Chromosomal inversion discovered in C3H/HeJ mice. JAX Notes. 2003;491:15
    • Latest
      J:333195 Chen R, et al., Impaired fertility in 4930590J08Rik mutant male mice is associated with defective sperm energy metabolism. FASEB J. 2022 Dec;36(12):e22634
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory