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Mettl21e Gene Detail
Summary
  • Symbol
    Mettl21e
  • Name
    methyltransferase like 21E
  • Synonyms
    4832428D23Rik, LOC381340
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685837
    NCBI Gene: 403183
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:44243230-44258121 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 23.63 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    655 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685837
 protein coding gene Chr1:44238651-44258260 (-)
129S1/SvImJ ENSMUSG00200001875
 protein coding gene Chr1:41872627-41887869 (-)
A/J ENSMUSG00195001828
 protein coding gene Chr1:41587989-41603041 (-)
AKR/J ENSMUSG00220003231
 protein coding gene Chr1:41582085-41597365 (-)
BALB/cJ ENSMUSG00180002995
 protein coding gene Chr1:41588859-41603747 (-)
C3H/HeJ ENSMUSG00175000039
 protein coding gene Chr1:41595611-41610658 (-)
C57BL/6NJ ENSMUSG00215002985
 protein coding gene Chr1:41563993-41578883 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014103
 protein coding gene Chr1:38745254-38762400 (-)
CAST/EiJ ENSTCUG00005000811
 protein coding gene Chr1:41662381-41677467 (-)
CBA/J ENSMUSG00210027161
 protein coding gene Chr1:41347179-41362230 (-)
DBA/2J ENSMUSG00185029623
 protein coding gene Chr1:42448373-42463431 (-)
FVB/NJ ENSMUSG00205003222
 protein coding gene Chr1:41529958-41545230 (-)
JF1/MsJ ENSUMUG00000001879
 protein coding gene Chr1:41660956-41676300 (-)
LP/J ENSMUSG00230000956
 protein coding gene Chr1:42474400-42489294 (-)
NOD/ShiLtJ ENSMUSG00190002284
 protein coding gene Chr1:41555648-41570923 (-)
NZO/HlLtJ ENSMUSG00225000541
 protein coding gene Chr1:45709500-45724396 (-)
PWK/PhJ ENSLUMG00010002270
 protein coding gene Chr1:41170245-41185731 (-)
SPRET/EiJ ENSMSPG00010012875
 protein coding gene Chr1:42761759-42776422 (-)
WSB/EiJ ENSIUOG00005003550
 protein coding gene Chr1:41524964-41540203 (-)



Homology
more
  • Human Ortholog
    METTL21EP, methyltransferase like 21E, pseudogene
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    METTL21EP, methyltransferase like 21E, pseudogene
  • Synonyms
    METTL21CP1
  • Links
    NCBI Gene ID: 121952
    UniProt: A6NDL7

  • Chr Location
    13q33.1; chr13:102880040-102896033 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Targeted
    1
  • Genomic Mutations
    1 involving Mettl21e
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    15 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    598
  • Tissues
    1
  • cDNA Data
    9
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000046828 Ensembl Gene Model | MGI Sequence Detail 14892 C57BL/6J ±  kb
transcript ENSMUST00000054801 Ensembl | MGI Sequence Detail 3211 Not Applicable  
polypeptide ENSMUSP00000056481 Ensembl | MGI Sequence Detail 244 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • EC
    2.1.1.-
  • InterPro Domains
    IPR019410 Lysine methyltransferase
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:162220 Magdaleno S, et al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory