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Tmem232 Gene Detail
Summary
  • Symbol
    Tmem232
  • Name
    transmembrane protein 232
  • Synonyms
    E130009J12Rik, LOC381107
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685786
    NCBI Gene: 381107
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:65562994-65847777 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 34.90 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1500 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685786
 protein coding gene Chr17:65562994-65848080 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023976
 protein coding gene Chr17:67359912-67665339 (-)
A/J MGP_AJ_G0023934
 protein coding gene Chr17:65373300-65637628 (-)
AKR/J MGP_AKRJ_G0023903
 protein coding gene Chr17:66269462-66564806 (-)
BALB/cJ MGP_BALBcJ_G0023935
 protein coding gene Chr17:65287786-65584198 (-)
C3H/HeJ MGP_C3HHeJ_G0023699
 protein coding gene Chr17:67155390-67450613 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024381
 protein coding gene Chr17:69998070-70294564 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021827
 protein coding gene Chr17:61443951-61683111 (-)
CAST/EiJ MGP_CASTEiJ_G0023181
 protein coding gene Chr17:67509063-67787363 (-)
CBA/J MGP_CBAJ_G0023675
 protein coding gene Chr17:72752713-73043941 (-)
DBA/2J MGP_DBA2J_G0023803
 protein coding gene Chr17:64116422-64398070 (-)
FVB/NJ MGP_FVBNJ_G0023769
 protein coding gene Chr17:63607367-63887158 (-)
LP/J MGP_LPJ_G0023885
 protein coding gene Chr17:68107165-68392833 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023797
 protein coding gene Chr17:72836345-73150892 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024425
 protein coding gene Chr17:66732094-67028131 (-)
PWK/PhJ MGP_PWKPhJ_G0022927
 protein coding gene Chr17:63384837-63659835 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022738
 protein coding gene Chr17:63420744-63699133 (-)
WSB/EiJ MGP_WSBEiJ_G0023247
 protein coding gene Chr17:67437477-67729431 (-)



Homology
more
  • Human Ortholog
    TMEM232, transmembrane protein 232
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM232, transmembrane protein 232
  • Links
    NCBI Gene ID: 642987
    neXtProt AC: NX_C9JQI7
    UniProt: C9JQI7

  • Chr Location
    5q22.1; chr5:110289233-110738956 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null males are infertile, exhibit reduced sperm count, abnormal sperm flagellum morphology and reduced sperm motility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000045036 Ensembl Gene Model | MGI Sequence Detail 284784 C57BL/6J ±  kb
    transcript ENSMUST00000086722 Ensembl | MGI Sequence Detail 2588 Not Applicable  
    polypeptide ENSMUSP00000083927 Ensembl | MGI Sequence Detail 675 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 3
    References
    more
    • Summaries
      All 26
      Gene Ontology 3
      Phenotypes 5
    • Earliest
      J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
    • Latest
      J:338029 He X, et al., Deficiency of the Tmem232 Gene Causes Male Infertility with Morphological Abnormalities of the Sperm Flagellum in Mice. Cells. 2023 Jun 13;12(12)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory