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Gfy Gene Detail
Summary
  • Symbol
    Gfy
  • Name
    golgi-associated olfactory signaling regulator
  • Synonyms
    Gm581, Goofy
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685427
    NCBI Gene: 100039953
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:44825773-44828993 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, Syntenic
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    27 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685427
 protein coding gene Chr7:44825773-44829021 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032206
 protein coding gene Chr7:45413060-45416310 (-)
A/J MGP_AJ_G0032185
 protein coding gene Chr7:44551170-44554409 (-)
AKR/J MGP_AKRJ_G0032121
 protein coding gene Chr7:45781643-45784891 (-)
BALB/cJ MGP_BALBcJ_G0032197
 protein coding gene Chr7:44550307-44553814 (-)
C3H/HeJ MGP_C3HHeJ_G0031913
 protein coding gene Chr7:46274844-46278079 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032689
 protein coding gene Chr7:47683803-47688462 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029703
 protein coding gene Chr7:47113189-47116426 (-)
CAST/EiJ MGP_CASTEiJ_G0031241
 protein coding gene Chr7:37666565-37669811 (-)
CBA/J MGP_CBAJ_G0031877
 protein coding gene Chr7:49244100-49249751 (-)
DBA/2J MGP_DBA2J_G0032035
 protein coding gene Chr7:44223398-44226903 (-)
FVB/NJ MGP_FVBNJ_G0031986
 protein coding gene Chr7:43998397-44001994 (-)
LP/J MGP_LPJ_G0032113
 protein coding gene Chr7:46096833-46100091 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032023
 protein coding gene Chr7:47960837-47963957 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032705
 protein coding gene Chr7:44996971-45000027 (-)
PWK/PhJ MGP_PWKPhJ_G0030964
 protein coding gene Chr7:37589534-37592840 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030801
 protein coding gene Chr7:33009641-33014191 (-)
WSB/EiJ MGP_WSBEiJ_G0031358
 protein coding gene Chr7:45491773-45496261 (-)



Homology
more
  • Human Ortholog
    GFY, golgi associated olfactory signaling regulator
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GFY, golgi associated olfactory signaling regulator
  • Synonyms
    Goofy
  • Links
    NCBI Gene ID: 100507003
    neXtProt AC: NX_I3L273
    UniProt: I3L273

  • Chr Location
    chr19:49423747-49428987 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display short olfactory epithelium (OE) cilia, reduced odorant induced local field potentials in the OE and impaired olfaction.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    920
  • Tissues
    21
  • cDNA Data
    5
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000095276 Ensembl Gene Model | MGI Sequence Detail 3221 C57BL/6J ±  kb
    transcript ENSMUST00000179443 Ensembl | MGI Sequence Detail 1849 Not Applicable  
    polypeptide ENSMUSP00000135927 Ensembl | MGI Sequence Detail 504 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5
    References
    more
    • Summaries
      All 15
      Developmental Gene Expression 2
      Gene Ontology 2
      Phenotypes 2
    • Earliest
      J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory