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H1f10 Gene Detail
Summary
  • Symbol
    H1f10
  • Name
    H1.10 linker histone
  • Synonyms
    H1-10, H1fx, H1X, LOC243529
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685307
    NCBI Gene: 243529
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:87957403-87958464 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 6, 39.13 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    4 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685307
protein coding gene Chr6:87957403-87958619 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031004
protein coding gene Chr6:89359911-89361071 (-)
A/J MGP_AJ_G0030970
protein coding gene Chr6:85908999-85910215 (-)
AKR/J MGP_AKRJ_G0030901
protein coding gene Chr6:88391961-88393177 (-)
BALB/cJ MGP_BALBcJ_G0030983
protein coding gene Chr6:85910255-85911471 (-)
C3H/HeJ MGP_C3HHeJ_G0030727
protein coding gene Chr6:96073412-96074628 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031440
protein coding gene Chr6:91743519-91744735 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028623
protein coding gene Chr6:84077258-84078472 (-)
CAST/EiJ MGP_CASTEiJ_G0030092
protein coding gene Chr6:88461121-88462336 (-)
CBA/J MGP_CBAJ_G0030667
protein coding gene Chr6:95291756-95292972 (-)
DBA/2J MGP_DBA2J_G0030823
protein coding gene Chr6:85199451-85200667 (-)
FVB/NJ MGP_FVBNJ_G0030776
protein coding gene Chr6:84395920-84397136 (-)
LP/J MGP_LPJ_G0030900
protein coding gene Chr6:89371868-89373084 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030809
protein coding gene Chr6:99426530-99427746 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031467
protein coding gene Chr6:88242039-88243254 (-)
PWK/PhJ MGP_PWKPhJ_G0029807
protein coding gene Chr6:84171224-84172440 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029635
protein coding gene Chr6:87057336-87058557 (-)
WSB/EiJ MGP_WSBEiJ_G0030173
protein coding gene Chr6:88690317-88691535 (-)



Homology
more
  • Human Ortholog
    H1-10, H1.10 linker histone
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    H1-10, H1.10 linker histone
  • Synonyms
    H1.10, H1FX, H1X
  • Links
    NCBI Gene ID: 8971
    neXtProt AC: NX_Q92522
    UniProt: Q92522

  • Chr Location
    3q21.3; chr3:129314771-129316286 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 243529 NCBI Gene Model | MGI Sequence Detail 1062 C57BL/6J ±  kb
    transcript NM_198622 RefSeq | MGI Sequence Detail 1126 Not Specified  
    polypeptide NP_941024 RefSeq | MGI Sequence Detail 188 Not Specified  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • InterPro Domains
      IPR005819 Linker histone H1/H5
      IPR005818 Linker histone H1/H5, domain H15
      IPR036390 Winged helix DNA-binding domain superfamily
      IPR036388 Winged helix-like DNA-binding domain superfamily
    Molecular
    Reagents
    less
    • All nucleic 2
      cDNA 1
      Primer pair 1

      Microarray probesets 2
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 5
      Gene Ontology 3
      Phenotypes 11
    • Earliest
      J:87486 Akeson EC, Chromosomal inversion discovered in C3H/HeJ mice. JAX Notes. 2003;491:15
    • Latest
      J:330636 Iwata S, et al., An efficient i-GONAD method for creating and maintaining lethal mutant mice using an inversion balancer identified from the C3H/HeJJcl strain. G3 (Bethesda). 2021;11(8)

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/12/2024
    MGI 6.23
    The Jackson Laboratory