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Cct8l1 Gene Detail
Summary
  • Symbol
    Cct8l1
  • Name
    chaperonin containing TCP1 subunit 8-like 1
  • Synonyms
    Gm443, LOC242891
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685289
    NCBI Gene: 242891
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:25721065-25723025 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 12.35 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    27 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685289
 protein coding gene Chr5:25721065-25723025 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029362
 protein coding gene Chr5:23314099-23316059 (+)
A/J MGP_AJ_G0029328
 protein coding gene Chr5:22495753-22497713 (+)
AKR/J MGP_AKRJ_G0029279
 protein coding gene Chr5:23416545-23418505 (+)
BALB/cJ MGP_BALBcJ_G0029339
 protein coding gene Chr5:23007452-23009412 (+)
C3H/HeJ MGP_C3HHeJ_G0029059
 protein coding gene Chr5:23517573-23519533 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029792
 protein coding gene Chr5:24845328-24847288 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027030
 protein coding gene Chr5:20415677-20417642 (+)
CAST/EiJ MGP_CASTEiJ_G0028471
 protein coding gene Chr5:22723028-22724988 (+)
CBA/J MGP_CBAJ_G0029026
 protein coding gene Chr5:25287168-25289128 (+)
DBA/2J MGP_DBA2J_G0029177
 protein coding gene Chr5:22767555-22769515 (+)
FVB/NJ MGP_FVBNJ_G0029135
 protein coding gene Chr5:22158965-22160925 (+)
LP/J MGP_LPJ_G0029261
 protein coding gene Chr5:23711710-23713670 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029164
 protein coding gene Chr5:26360706-26362666 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029826
 protein coding gene Chr5:23038335-23040295 (+)
PWK/PhJ MGP_PWKPhJ_G0028195
 protein coding gene Chr5:21889085-21891045 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028026
 protein coding gene Chr5:22390323-22392281 (+)
WSB/EiJ MGP_WSBEiJ_G0028551
 protein coding gene Chr5:23118312-23120272 (+)



Homology
more
  • Human Ortholog
    CCT8L1P, chaperonin containing TCP1 subunit 8 like 1, pseudogene
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCT8L1P, chaperonin containing TCP1 subunit 8 like 1, pseudogene
  • Synonyms
    CCT8L1
  • Links
    NCBI Gene ID: 155100
    UniProt: A6NM43

  • Chr Location
    7q36.1; chr7:152445217-152447276 (+)  GRCh38
  • Human Ortholog
    CCT8L2, chaperonin containing TCP1 subunit 8 like 2
  • Synonyms
    CESK1
  • Links
    NCBI Gene ID: 150160
    neXtProt AC: NX_Q96SF2
    UniProt: Q96SF2

  • Chr Location
    22q11.1; chr22:16590751-16592810 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    2
  • Radiation induced
    2
  • Spontaneous
    1
  • Targeted
    3
  • Genomic Mutations
    5 involving Cct8l1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    22 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 242891 NCBI Gene Model | MGI Sequence Detail 1961 C57BL/6J ±  kb
transcript NM_198621 RefSeq | MGI Sequence Detail 1967 C57BL/6  
polypeptide NP_941023 RefSeq | MGI Sequence Detail 562 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1)
    IPR002423 Chaperonin Cpn60/GroEL/TCP-1 family
    IPR002194 Chaperonin TCP-1, conserved site
    IPR027409 GroEL-like apical domain superfamily
    IPR027413 GroEL-like equatorial domain superfamily
    IPR027410 TCP-1-like chaperonin intermediate domain superfamily
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Diseases 1
    Gene Ontology 1
    Phenotypes 13
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:119563 Alt B, et al., Arteries define the position of the thyroid gland during its developmental relocalisation. Development. 2006 Oct;133(19):3797-804
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory