About   Help   FAQ
Prss47 Gene Detail
Summary
  • Symbol
    Prss47
  • Name
    serine protease 47
  • Synonyms
    Gm274, LOC218304
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685120
    NCBI Gene: 218304
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:65192420-65200574 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 34.21 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    321 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685120
 protein coding gene Chr13:65192420-65200685 (-)
129S1/SvImJ ENSMUSG00200012232
 protein coding gene Chr13:61297767-61305912 (-)
A/J ENSMUSG00195025992
 protein coding gene Chr13:61462547-61470667 (-)
AKR/J ENSMUSG00220035677
 protein coding gene Chr13:60542986-60551125 (-)
BALB/cJ ENSMUSG00180021742
 protein coding gene Chr13:61762015-61770137 (-)
C3H/HeJ ENSMUSG00175007710
 protein coding gene Chr13:61587845-61596010 (-)
C57BL/6NJ ENSMUSG00215006489
 protein coding gene Chr13:61604134-61612288 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018648
 protein coding gene Chr13:60350301-60358451 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210008804
 protein coding gene Chr13:61787312-61795471 (-)
DBA/2J ENSMUSG00185006768
 protein coding gene Chr13:62618392-62626558 (-)
FVB/NJ ENSMUSG00205022702
 protein coding gene Chr13:60771950-60780072 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230033369
 protein coding gene Chr13:71956330-71964432 (-)
NOD/ShiLtJ ENSMUSG00190035357
 protein coding gene Chr13:61527752-61535916 (-)
NZO/HlLtJ ENSMUSG00225045211
 protein coding gene Chr13:65678953-65687107 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    PRSS47P, serine protease 47, pseudogene
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRSS47P, serine protease 47, pseudogene
  • Synonyms
    PRSS47
  • Links
    NCBI Gene ID: 138652
    UniProt: A8MTI9

  • Chr Location
    9q22.31; chr9:92177163-92191156 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000090658 Ensembl Gene Model | MGI Sequence Detail 8155 C57BL/6J ±  kb
    transcript ENSMUST00000203968 Ensembl | MGI Sequence Detail 1353 Not Applicable  
    polypeptide ENSMUSP00000145196 Ensembl | MGI Sequence Detail 395 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • EC
      3.4.21.1
    • InterPro Domains
      IPR001314 Peptidase S1A, chymotrypsin family
      IPR009003 Peptidase S1, PA clan
      IPR001254 Serine proteases, trypsin domain
      IPR033116 Serine proteases, trypsin family, serine active site
    References
    more
    • Summaries
      All 21
      Gene Ontology 4
      Phenotypes 8
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory