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Myrfl Gene Detail
Summary
  • Symbol
    Myrfl
  • Name
    myelin regulatory factor-like
  • Synonyms
    Gm239, LOC237558
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685085
    NCBI Gene: 237558
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:116612450-116732784 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 64.90 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1562 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685085
 protein coding gene Chr10:116612440-116732824 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017747
 protein coding gene Chr10:119577111-119699080 (-)
A/J MGP_AJ_G0017723
 protein coding gene Chr10:114969378-115089602 (-)
AKR/J MGP_AKRJ_G0017685
 protein coding gene Chr10:118297095-118420309 (-)
BALB/cJ MGP_BALBcJ_G0017686
 protein coding gene Chr10:115367531-115488330 (-)
C3H/HeJ MGP_C3HHeJ_G0017511
 protein coding gene Chr10:118534684-118658088 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018143
 protein coding gene Chr10:123736111-123864260 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015823
 protein coding gene Chr10:109559492-109679939 (-)
CAST/EiJ MGP_CASTEiJ_G0017073
 protein coding gene Chr10:118827977-118961384 (-)
CBA/J MGP_CBAJ_G0017480
 protein coding gene Chr10:128585301-128735536 (-)
DBA/2J MGP_DBA2J_G0017585
 protein coding gene Chr10:114108107-114229582 (-)
FVB/NJ MGP_FVBNJ_G0017580
 protein coding gene Chr10:113060440-113182285 (-)
LP/J MGP_LPJ_G0017660
 protein coding gene Chr10:120163286-120291519 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017609
 protein coding gene Chr10:131474198-131608559 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018181
 protein coding gene Chr10:118374663-118499839 (-)
PWK/PhJ MGP_PWKPhJ_G0016855
 protein coding gene Chr10:114161733-114332217 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016645
 protein coding gene Chr10:117182052-117312048 (-)
WSB/EiJ MGP_WSBEiJ_G0017133
 protein coding gene Chr10:118557824-118695766 (-)



Homology
more
  • Human Ortholog
    MYRFL, myelin regulatory factor like
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MYRFL, myelin regulatory factor like
  • Synonyms
    bcm1377, C12orf15, C12orf28
  • Links
    NCBI Gene ID: 196446
    neXtProt AC: NX_Q96LU7
    UniProt: Q96LU7

  • Chr Location
    12q15; chr12:69825227-69959097 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 237558 NCBI Gene Model | MGI Sequence Detail 120335 C57BL/6J ±  kb
transcript NM_001033333 RefSeq | MGI Sequence Detail 3114 C57BL/6  
polypeptide Q3UN70 UniProt | EBI | MGI Sequence Detail 904 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000060018 myelin regulatory factor-like protein
    (term hierarchy)
  • InterPro Domains
    IPR030392 Intramolecular chaperone auto-processing domain
    IPR025719 Myelin gene regulatory factor C-terminal domain 2
    IPR026932 Myelin gene regulatory factor, ICA domain
    IPR024061 NDT80 DNA-binding domain
    IPR037141 NDT80 DNA-binding domain superfamily
    IPR008967 p53-like transcription factor, DNA-binding domain superfamily
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Gene Ontology 1
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:274872 Ingham NJ, et al., Mouse screen reveals multiple new genes underlying mouse and human hearing loss. PLoS Biol. 2019 Apr;17(4):e3000194
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory