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Rfpl4b Gene Detail
Summary
  • Symbol
    Rfpl4b
  • Name
    ret finger protein-like 4B
  • Synonyms
    Gm3037, Gm62, LOC215919
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684908
    NCBI Gene: 215919
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr10:38696537-38697775 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 10, 19.98 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    7 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684908
protein coding gene Chr10:38696537-38697775 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017146
protein coding gene Chr10:37296202-37297440 (-)
A/J MGP_AJ_G0017123
protein coding gene Chr10:36320868-36322106 (-)
AKR/J MGP_AKRJ_G0017083
protein coding gene Chr10:36788300-36789538 (-)
BALB/cJ MGP_BALBcJ_G0017086
protein coding gene Chr10:36346663-36347901 (-)
C3H/HeJ MGP_C3HHeJ_G0016906
protein coding gene Chr10:37121863-37123101 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017544
protein coding gene Chr10:38459270-38460508 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015241
protein coding gene Chr10:34323660-34324897 (-)
CAST/EiJ MGP_CASTEiJ_G0016485
protein coding gene Chr10:37277351-37278589 (-)
CBA/J MGP_CBAJ_G0016880
protein coding gene Chr10:40237505-40238743 (-)
DBA/2J MGP_DBA2J_G0016985
protein coding gene Chr10:35841449-35842687 (-)
FVB/NJ MGP_FVBNJ_G0016980
protein coding gene Chr10:35350118-35351356 (-)
LP/J MGP_LPJ_G0017062
protein coding gene Chr10:37271218-37272456 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017010
protein coding gene Chr10:41098086-41099324 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017580
protein coding gene Chr10:36779394-36780632 (-)
PWK/PhJ MGP_PWKPhJ_G0016266
protein coding gene Chr10:35670460-35671699 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016050
protein coding gene Chr10:36565372-36566601 (-)
WSB/EiJ MGP_WSBEiJ_G0016548
protein coding gene Chr10:37075967-37077205 (-)



Homology
more
  • Human Ortholog
    RFPL4B, ret finger protein like 4B
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RFPL4B, ret finger protein like 4B
  • Synonyms
    RNF211
  • Links
    NCBI Gene ID: 442247
    neXtProt AC: NX_Q6ZWI9
    UniProt: Q6ZWI9

  • Chr Location
    6q21; chr6:112347330-112351294 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Rfpl4b
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 215919 NCBI Gene Model | MGI Sequence Detail 1239 C57BL/6J ±  kb
transcript NM_001177783 RefSeq | MGI Sequence Detail 1054 C57BL/6  
polypeptide NP_001171254 RefSeq | MGI Sequence Detail 266 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR043136 B30.2/SPRY domain superfamily
    IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
    IPR013083 Zinc finger, RING/FYVE/PHD-type
    IPR001841 Zinc finger, RING-type
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 3
Other
Accession IDs
less
MGI:3781215
References
more
  • Summaries
    All 25
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory