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Slc25a43 Gene Detail
Summary
  • Symbol
    Slc25a43
  • Name
    solute carrier family 25, member 43
  • Synonyms
    LOC194744
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684854
    NCBI Gene: 194744
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:36007312-36040855 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 21.15 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    726 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684854
 protein coding gene ChrX:36007223-36040960 (+)
129S1/SvImJ ENSMUSG00200015349
 protein coding gene ChrX:20116731-20150281 (+)
A/J ENSMUSG00195024776
 protein coding gene ChrX:22787257-22820821 (+)
AKR/J ENSMUSG00220017391
 protein coding gene ChrX:19898724-19932280 (+)
BALB/cJ ENSMUSG00180011921
 protein coding gene ChrX:20345624-20379189 (+)
C3H/HeJ ENSMUSG00175022542
 protein coding gene ChrX:23487761-23521318 (+)
C57BL/6NJ ENSMUSG00215022378
 protein coding gene ChrX:20538975-20572524 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032991
 protein coding gene ChrX:29961677-29994971 (+)
CAST/EiJ ENSTCUG00005031549
 protein coding gene ChrX:22432150-22465698 (+)
CBA/J ENSMUSG00210034184
 protein coding gene ChrX:20783658-20817210 (+)
DBA/2J ENSMUSG00185024230
 protein coding gene ChrX:31364576-31398126 (+)
FVB/NJ ENSMUSG00205016831
 protein coding gene ChrX:19459460-19493026 (+)
JF1/MsJ ENSUMUG00000023712
 protein coding gene ChrX:50474985-50508566 (+)
LP/J ENSMUSG00230011056
 protein coding gene ChrX:37856836-37890383 (+)
NOD/ShiLtJ ENSMUSG00190024180
 protein coding gene ChrX:20057823-20091373 (+)
NZO/HlLtJ ENSMUSG00225038523
 protein coding gene ChrX:43063232-43096776 (+)
PWK/PhJ ENSLUMG00010016040
 protein coding gene ChrX:20184197-20218546 (+)
SPRET/EiJ ENSMSPG00010017046
 protein coding gene ChrX:21417641-21450807 (+)
WSB/EiJ ENSIUOG00005037334
 protein coding gene ChrX:20972745-21007068 (+)



Homology
more
  • Human Ortholog
    SLC25A43, solute carrier family 25 member 43
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC25A43, solute carrier family 25 member 43
  • Links
    NCBI Gene ID: 203427
    UniProt: Q8WUT9

  • Chr Location
    Xq24; chrX:119399336-119454478 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    601
  • Tissues
    4
  • cDNA Data
    7
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037636 Ensembl Gene Model | MGI Sequence Detail 33544 C57BL/6J ±  kb
transcript ENSMUST00000047655 Ensembl | MGI Sequence Detail 1111 Not Applicable  
polypeptide ENSMUSP00000035392 Ensembl | MGI Sequence Detail 341 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000032076 solute carrier family 25 member 43
    (term hierarchy)
  • InterPro Domains
    IPR002067 Mitochondrial carrier protein
    IPR023395 Mitochondrial carrier protein domain superfamily
    IPR018108 Mitochondrial carrier protein, transmembrane region
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory