About   Help   FAQ
Grip2 Gene Detail
Summary
  • Symbol
    Grip2
  • Name
    glutamate receptor interacting protein 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2681173
    NCBI Gene: 243547
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:91738490-91804231 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 40.80 cM, cytoband D2
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    399 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2681173
 protein coding gene Chr6:91738433-91820884 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031051
 protein coding gene Chr6:93372360-93461337 (-)
A/J MGP_AJ_G0031020
 protein coding gene Chr6:89816149-89901005 (-)
AKR/J MGP_AKRJ_G0030951
 protein coding gene Chr6:92306503-92389709 (-)
BALB/cJ MGP_BALBcJ_G0031031
 protein coding gene Chr6:89760614-89866621 (-)
C3H/HeJ MGP_C3HHeJ_G0030677
 protein coding gene Chr6:92061859-92126824 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031490
 protein coding gene Chr6:95795198-95862914 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028657
 protein coding gene Chr6:87799534-87869364 (-)
CAST/EiJ MGP_CASTEiJ_G0030138
 protein coding gene Chr6:92431995-92520011 (-)
CBA/J MGP_CBAJ_G0030717
 protein coding gene Chr6:99362192-99431459 (-)
DBA/2J MGP_DBA2J_G0030870
 protein coding gene Chr6:88999692-89063709 (-)
FVB/NJ MGP_FVBNJ_G0030824
 protein coding gene Chr6:88212639-88296696 (-)
LP/J MGP_LPJ_G0030950
 protein coding gene Chr6:93335868-93403831 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030858
 protein coding gene Chr6:103413136-103499845 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031517
 protein coding gene Chr6:92155077-92238341 (-)
PWK/PhJ MGP_PWKPhJ_G0029854
 protein coding gene Chr6:87953940-88022976 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029683
 protein coding gene Chr6:91065327-91151751 (-)
WSB/EiJ MGP_WSBEiJ_G0030222
 protein coding gene Chr6:92632286-92697822 (-)



Homology
more
  • Human Ortholog
    GRIP2, glutamate receptor interacting protein 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GRIP2, glutamate receptor interacting protein 2
  • Links
    NCBI Gene ID: 80852
    neXtProt AC: NX_Q9C0E4
    UniProt: Q9C0E4

  • Chr Location
    3p25.1; chr3:14489107-14603017 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotypes from multigenic genotypes
    13 phenotype references
Homozygous null mice are born in numbers expected by the Mendelian ratio and show no overt phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    718
  • Tissues
    3
  • cDNA Data
    22
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030098 Ensembl Gene Model | MGI Sequence Detail 65742 C57BL/6J ±  kb
transcript ENSMUST00000162300 Ensembl | MGI Sequence Detail 5206 Not Applicable  
polypeptide ENSMUSP00000124709 Ensembl | MGI Sequence Detail 1042 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    cDNA 22

    Microarray probesets 2
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 13
  • Earliest
    J:87486 Akeson EC, Chromosomal inversion discovered in C3H/HeJ mice. JAX Notes. 2003;491:15
  • Latest
    J:330636 Iwata S, et al., An efficient i-GONAD method for creating and maintaining lethal mutant mice using an inversion balancer identified from the C3H/HeJJcl strain. G3 (Bethesda). 2021;11(8)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory