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Cyp26c1 Gene Detail
Summary
  • Symbol
    Cyp26c1
  • Name
    cytochrome P450, family 26, subfamily c, polypeptide 1
  • Synonyms
    EG546726
Location &
Maps
more
  • Sequence Map
    Chr19:37674029-37681846 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 32.36 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    347 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2679699
 protein coding gene Chr19:37673560-37681846 (+)
129S1/SvImJ ENSMUSG00200027290
 protein coding gene Chr19:34468653-34476472 (+)
A/J ENSMUSG00195011464
 protein coding gene Chr19:34568188-34576006 (+)
AKR/J ENSMUSG00220018564
 protein coding gene Chr19:34449674-34457493 (+)
BALB/cJ ENSMUSG00180031211
 protein coding gene Chr19:34896126-34903943 (+)
C3H/HeJ ENSMUSG00175036559
 protein coding gene Chr19:34329719-34337514 (+)
C57BL/6NJ ENSMUSG00215010174
 protein coding gene Chr19:34340337-34348154 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022917
 protein coding gene Chr19:34265456-34273225 (+)
CAST/EiJ ENSTCUG00005015229
 protein coding gene Chr19:34005049-34013264 (+)
CBA/J ENSMUSG00210033621
 protein coding gene Chr19:34408980-34416772 (+)
DBA/2J ENSMUSG00185029582
 protein coding gene Chr19:34929160-34936951 (+)
FVB/NJ ENSMUSG00205006185
 protein coding gene Chr19:34174649-34182467 (+)
JF1/MsJ ENSUMUG00000024005
 protein coding gene Chr19:35068496-35076326 (+)
LP/J ENSMUSG00230030753
 protein coding gene Chr19:35740480-35748296 (+)
NOD/ShiLtJ ENSMUSG00190010638
 protein coding gene Chr19:34306472-34314288 (+)
NZO/HlLtJ ENSMUSG00225029044
 protein coding gene Chr19:39290303-39298118 (+)
PWK/PhJ ENSLUMG00010000758
 protein coding gene Chr19:34451236-34459091 (+)
SPRET/EiJ ENSMSPG00010022460
 protein coding gene Chr19:34175244-34183118 (+)
WSB/EiJ ENSIUOG00005035250
 protein coding gene Chr19:33815538-33823354 (+)



Homology
more
  • Human Ortholog
    CYP26C1, cytochrome P450 family 26 subfamily C member 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP26C1, cytochrome P450 family 26 subfamily C member 1
  • Synonyms
    FFDD4
  • Links
    NCBI Gene ID: 340665
    UniProt: Q6V0L0

  • Chr Location
    10q23.33; chr10:93060798-93069540 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Mice homozygous for a knock-out allele are viable and exhibit normal CNS development with no apparent anatomical defects.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    729
  • Tissues
    60
  • cDNA Data
    5
  • Literature Summary
    31
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000062432 Ensembl Gene Model | MGI Sequence Detail 7818 C57BL/6J ±  kb
transcript ENSMUST00000073391 Ensembl | MGI Sequence Detail 1747 Not Applicable  
polypeptide ENSMUSP00000073105 Ensembl | MGI Sequence Detail 518 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 5
    Primer pair 4
    Other 2

    Microarray probesets 1
Other
Accession IDs
less
MGI:3643384
References
more
  • Summaries
    All 52
    Developmental Gene Expression 31
    Gene Ontology 7
    Phenotypes 4
  • Earliest
    J:85714 Tahayato A, et al., Cyp26C1 encodes a novel retinoic acid-metabolizing enzyme expressed in the hindbrain, inner ear, first branchial arch and tooth buds during murine development. Gene Expr Patterns. 2003 Aug;3(4):449-54
  • Latest
    J:390120 Trowe MO, et al., Mesenchymal WNT signaling coordinates epithelial and mesenchymal differentiation in the developing murine ureter. Cell Commun Signal. 2026 Jul 21;24(1)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory