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Cetn4 Gene Detail
Summary
  • Symbol
    Cetn4
  • Name
    centrin 4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2677454
    NCBI Gene: 207175
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:37362776-37366595 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 3, 18.41 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    11 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2677454
protein coding gene Chr3:37361898-37366857 (-)
129S1/SvImJ ENSMUSG00200005458
protein coding gene Chr3:34112970-34117804 (-)
A/J ENSMUSG00195001381
protein coding gene Chr3:34082863-34087698 (-)
AKR/J ENSMUSG00220000471
protein coding gene Chr3:34142832-34147666 (-)
BALB/cJ ENSMUSG00180002428
protein coding gene Chr3:34216501-34221460 (-)
C3H/HeJ ENSMUSG00175003284
protein coding gene Chr3:34112864-34117699 (-)
C57BL/6NJ ENSMUSG00215001463
protein coding gene Chr3:34490504-34495465 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024947
protein coding gene Chr3:32127317-32131918 (-)
CAST/EiJ ENSTCUG00005000809
protein coding gene Chr3:33953802-33958764 (-)
CBA/J ENSMUSG00210001477
protein coding gene Chr3:34170424-34175259 (-)
DBA/2J ENSMUSG00185001282
protein coding gene Chr3:34368645-34373481 (-)
FVB/NJ ENSMUSG00205000388
protein coding gene Chr3:33534835-33539794 (-)
JF1/MsJ ENSUMUG00000000301
protein coding gene Chr3:33903649-33908605 (-)
LP/J ENSMUSG00230019884
protein coding gene Chr3:36308356-36360609 (-)
NOD/ShiLtJ ENSMUSG00190001339
protein coding gene Chr3:34410724-34415559 (-)
NZO/HlLtJ ENSMUSG00225006873
protein coding gene Chr3:38919219-38971471 (-)
PWK/PhJ ENSLUMG00010000580
protein coding gene Chr3:33948414-33953363 (-)
SPRET/EiJ ENSMSPG00010000497
protein coding gene Chr3:34343374-34347412 (-)
WSB/EiJ ENSIUOG00005013091
protein coding gene Chr3:34417946-34422786 (-)



Homology
more
  • Human Ortholog
    CETN4P, centrin 4, pseudogene
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CETN4P, centrin 4, pseudogene
  • Links
    NCBI Gene ID: 729338

  • Chr Location
    4q27; chr4:122730189-122732458 (-)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    10
  • Endonuclease-mediated
    1
  • Gene trapped
    6
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    2 involving Cetn4
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 207175 NCBI Gene Model | MGI Sequence Detail 3820 C57BL/6J ±  kb
transcript NM_145825 RefSeq | MGI Sequence Detail 1059 C57BL/6  
polypeptide Q8K4K1 UniProt | EBI | MGI Sequence Detail 168 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site
    IPR050230 Calmodulin/Myosin light chain/Troponin C-like
    IPR018247 EF-Hand 1, calcium-binding site
    IPR002048 EF-hand domain
    IPR011992 EF-hand domain pair
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 4
References
more
  • Summaries
    All 37
    Diseases 1
    Gene Ontology 7
    Phenotypes 12
  • Earliest
    J:64276 Lyon MF, et al., Dose-response curves for radiation-induced gene mutations in mouse oocytes and their interpretation. Mutat Res. 1979 Nov;63(1):161-73
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory