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Mir24-1 Gene Detail
Summary
  • Symbol
    Mir24-1
  • Name
    microRNA 24-1
  • Synonyms
    miR-24-1, Mirn189, Mirn24, Mirn24-1, mmu-mir-24-1
  • Feature Type
    miRNA gene
  • IDs
    MGI:2676899
    NCBI Gene: 387142
  • Member of
    Mirc22 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:63449022-63449089 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 32.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    29 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676899
 miRNA gene Chr13:63449022-63449089 (+)
129S1/SvImJ MGP_129S1SvImJ_G0008080
 miRNA gene Chr13:63261301-63261368 (+)
A/J MGP_AJ_G0008070
 miRNA gene Chr13:60959467-60959534 (+)
AKR/J MGP_AKRJ_G0008049
 miRNA gene Chr13:63001602-63001669 (+)
BALB/cJ MGP_BALBcJ_G0008053
 miRNA gene Chr13:61387899-61387966 (+)
C3H/HeJ MGP_C3HHeJ_G0007996
 miRNA gene Chr13:62533817-62533884 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008238
 miRNA gene Chr13:65322051-65322118 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007341
 miRNA gene Chr13:58633610-58633677 (+)
CAST/EiJ MGP_CASTEiJ_G0007879
 miRNA gene Chr13:62536805-62536872 (+)
CBA/J MGP_CBAJ_G0007965
 miRNA gene Chr13:67842772-67842839 (+)
DBA/2J MGP_DBA2J_G0007999
 miRNA gene Chr13:60802391-60802458 (+)
FVB/NJ MGP_FVBNJ_G0008021
 miRNA gene Chr13:59919724-59919791 (+)
LP/J MGP_LPJ_G0008082
 miRNA gene Chr13:63538111-63538178 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0007991
 miRNA gene Chr13:66815981-66816048 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008236
 miRNA gene Chr13:62306240-62306307 (+)
PWK/PhJ MGP_PWKPhJ_G0007800
 miRNA gene Chr13:60360705-60360772 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007695
 miRNA gene Chr13:60461550-60461617 (+)
WSB/EiJ MGP_WSBEiJ_G0007951
 miRNA gene Chr13:62796451-62796518 (+)



Homology
more
  • Human Ortholog
    MIR24-1, microRNA 24-1
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR24-1, microRNA 24-1
  • Synonyms
    MIR189, miR-24-1, MIRN24-1, miRNA24-1
  • Links
    NCBI Gene ID: 407012

  • Chr Location
    chr9:95086021-95086088 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    3 phenotypes from multigenic genotypes
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele of Mir24-1 and Mir24-2 exhibit increased keratinocyte proliferation and hair regrowth.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    768
  • Tissues
    26
  • Literature Summary
    17
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      24
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 387142 NCBI Gene Model | MGI Sequence Detail 68 C57BL/6J ±  kb
    transcript NR_029575 RefSeq | MGI Sequence Detail 68 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 6
      Primer pair 3
      Other 3
    Other Database
    Links
    less
    miRBase MI0000231
    Other
    Accession IDs
    less
    MGI:2676853
    References
    more
    • Summaries
      All 61
      Developmental Gene Expression 17
      Gene Ontology 8
      Phenotypes 7
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:344664 Sprenkle NT, et al., The miR-23-27-24 clusters drive lipid-associated macrophage proliferation in obese adipose tissue. Cell Rep. 2023 Aug 29;42(8):112928
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory