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Mir150 Gene Detail
Summary
  • Symbol
    Mir150
  • Name
    microRNA 150
  • Synonyms
    Mirn150, mmu-mir-150
  • Feature Type
    miRNA gene
  • IDs
    MGI:2676835
    NCBI Gene: 387168
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr7:44771181-44771245 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 29.14 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    51 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676835
 miRNA gene Chr7:44771181-44771245 (+)
129S1/SvImJ MGP_129S1SvImJ_G0009004
 miRNA gene Chr7:45357117-45357181 (+)
A/J MGP_AJ_G0008986
 miRNA gene Chr7:44494479-44494543 (+)
AKR/J MGP_AKRJ_G0008975
 miRNA gene Chr7:45723949-45724013 (+)
BALB/cJ MGP_BALBcJ_G0008973
 miRNA gene Chr7:44492951-44493015 (+)
C3H/HeJ MGP_C3HHeJ_G0008911
 miRNA gene Chr7:46220414-46220478 (+)
C57BL/6NJ MGP_C57BL6NJ_G0009210
 miRNA gene Chr7:47625381-47625445 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0008098
 miRNA gene Chr7:47057997-47058061 (+)
CAST/EiJ MGP_CASTEiJ_G0008749
 miRNA gene Chr7:37604123-37604187 (+)
CBA/J MGP_CBAJ_G0008882
 miRNA gene Chr7:49181047-49181111 (+)
DBA/2J MGP_DBA2J_G0008910
 miRNA gene Chr7:44164178-44164242 (+)
FVB/NJ MGP_FVBNJ_G0008930
 miRNA gene Chr7:43942110-43942174 (+)
LP/J MGP_LPJ_G0009007
 miRNA gene Chr7:46038289-46038353 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0008895
 miRNA gene Chr7:47900167-47900231 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0009180
 miRNA gene Chr7:44940296-44940360 (+)
PWK/PhJ MGP_PWKPhJ_G0008679
 miRNA gene Chr7:37529398-37529462 (+)
SPRET/EiJ MGP_SPRETEiJ_G0008521
 miRNA gene Chr7:32952763-32952827 (+)
WSB/EiJ MGP_WSBEiJ_G0008845
 miRNA gene Chr7:45430626-45430690 (+)



Homology
more
  • Human Ortholog
    MIR150, microRNA 150
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR150, microRNA 150
  • Synonyms
    mir-150, MIRN150, miRNA150
  • Links
    NCBI Gene ID: 406942

  • Chr Location
    chr19:49500785-49500868 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 3 alleles in 2 genetic backgrounds
    26 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increased B-1 B cell number, decreased B-2 B cell number, and enhanced humoral immune responses.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    3
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      24
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 387168 NCBI Gene Model | MGI Sequence Detail 65 C57BL/6J ±  kb
    transcript NR_029560 RefSeq | MGI Sequence Detail 65 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 2
      Primer pair 1
      Other 1
    Other Database
    Links
    less
    miRBase MI0000172
    References
    more
    • Summaries
      All 65
      Developmental Gene Expression 4
      Gene Ontology 9
      Phenotypes 26
    • Earliest
      J:84907 Lagos-Quintana M, et al., Identification of tissue-specific microRNAs from mouse. Curr Biol. 2002 Apr 30;12(9):735-9
    • Latest
      J:343342 Menoret A, et al., Antigen-specific downregulation of miR-150 in CD4 T cells promotes cell survival. Front Immunol. 2023;14:1102403
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory