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Mir138-1 Gene Detail
Summary
  • Symbol
    Mir138-1
  • Name
    microRNA 138-1
  • Synonyms
    Mirn138, Mirn138-1, mmu-mir-138-1
  • Feature Type
    miRNA gene
  • IDs
    MGI:2676823
    NCBI Gene: 387156
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:122511941-122512039 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 73.05 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676823
 miRNA gene Chr9:122511941-122512039 (+)
129S1/SvImJ MGP_129S1SvImJ_G0009251
 miRNA gene Chr9:125680142-125680240 (+)
A/J MGP_AJ_G0009231
 miRNA gene Chr9:120875680-120875778 (+)
AKR/J MGP_AKRJ_G0009221
 miRNA gene Chr9:124128715-124128813 (+)
BALB/cJ MGP_BALBcJ_G0009215
 miRNA gene Chr9:120798012-120798110 (+)
C3H/HeJ MGP_C3HHeJ_G0009155
 miRNA gene Chr9:124559962-124560060 (+)
C57BL/6NJ MGP_C57BL6NJ_G0009458
 miRNA gene Chr9:129137600-129137698 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0008986
 miRNA gene Chr9:124588379-124588477 (+)
CBA/J MGP_CBAJ_G0009122
 miRNA gene Chr9:133861097-133861195 (+)
DBA/2J MGP_DBA2J_G0009152
 miRNA gene Chr9:120323334-120323432 (+)
FVB/NJ MGP_FVBNJ_G0009169
 miRNA gene Chr9:119244779-119244877 (+)
LP/J MGP_LPJ_G0009249
 miRNA gene Chr9:126018675-126018773 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0009136
 miRNA gene Chr9:134726899-134726997 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0009428
 miRNA gene Chr9:124578552-124578650 (+)
PWK/PhJ MGP_PWKPhJ_G0008911
 miRNA gene Chr9:120775678-120775776 (+)
SPRET/EiJ MGP_SPRETEiJ_G0008748
 miRNA gene Chr9:124655921-124656019 (+)
WSB/EiJ MGP_WSBEiJ_G0009080
 miRNA gene Chr9:124424891-124424989 (+)



Homology
more
  • Human Ortholog
    MIR138-1, microRNA 138-1
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR138-1, microRNA 138-1
  • Synonyms
    mir-138-1, MIRN138-1
  • Links
    NCBI Gene ID: 406929

  • Chr Location
    chr3:44114212-44114310 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Mice homozygous for a targeted deletion are viable with no observed pathologies.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    759
  • Tissues
    13
  • Literature Summary
    9
Sequences &
Gene Models
less
  • All Sequences
    23
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 387156 NCBI Gene Model | MGI Sequence Detail 99 C57BL/6J ±  kb
transcript NR_029819 RefSeq | MGI Sequence Detail 99 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 3
    Primer pair 1
    Other 2
Other Database
Links
less
miRBase MI0000722
References
more
  • Summaries
    All 25
    Developmental Gene Expression 9
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:84907 Lagos-Quintana M, et al., Identification of tissue-specific microRNAs from mouse. Curr Biol. 2002 Apr 30;12(9):735-9
  • Latest
    J:318524 Bai XZ, et al., MicroRNA-138 Aggravates Inflammatory Responses of Macrophages by Targeting SIRT1 and Regulating the NF-kappaB and AKT Pathways. Cell Physiol Biochem. 2018;49(2):489-500
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory