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Mir137 Gene Detail
Summary
  • Symbol
    Mir137
  • Name
    microRNA 137
  • Synonyms
    Mirn137, mmu-mir-137
  • Feature Type
    miRNA gene
  • IDs
    MGI:2676822
    NCBI Gene: 387155
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr3:118227506-118227578 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 3, 51.71 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676822
miRNA gene Chr3:118227506-118227578 (+)
129S1/SvImJ MGP_129S1SvImJ_G0008676
miRNA gene Chr3:120458438-120458510 (+)
A/J MGP_AJ_G0008666
miRNA gene Chr3:116503653-116503725 (+)
AKR/J MGP_AKRJ_G0008656
miRNA gene Chr3:119429880-119429952 (+)
BALB/cJ MGP_BALBcJ_G0008654
miRNA gene Chr3:116326798-116326870 (+)
C3H/HeJ MGP_C3HHeJ_G0008594
miRNA gene Chr3:119843664-119843736 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008868
miRNA gene Chr3:124842865-124842937 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007832
miRNA gene Chr3:112069305-112069377 (+)
CAST/EiJ MGP_CASTEiJ_G0008446
miRNA gene Chr3:119159055-119159127 (+)
CBA/J MGP_CBAJ_G0008558
miRNA gene Chr3:129143543-129143615 (+)
DBA/2J MGP_DBA2J_G0008591
miRNA gene Chr3:115696527-115696599 (+)
FVB/NJ MGP_FVBNJ_G0008615
miRNA gene Chr3:113315518-113315590 (+)
LP/J MGP_LPJ_G0008684
miRNA gene Chr3:122019411-122019483 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0008578
miRNA gene Chr3:136595647-136595719 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008849
miRNA gene Chr3:118985817-118985889 (+)
PWK/PhJ MGP_PWKPhJ_G0008371
miRNA gene Chr3:115338245-115338317 (+)
SPRET/EiJ MGP_SPRETEiJ_G0008225
miRNA gene Chr3:117039857-117039929 (+)
WSB/EiJ MGP_WSBEiJ_G0008531
miRNA gene Chr3:119699193-119699265 (+)



Homology
more
  • Human Ortholog
    MIR137, microRNA 137
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR137, microRNA 137
  • Synonyms
    miR-137, MIRN137
  • Links
    NCBI Gene ID: 406928

  • Chr Location
    chr1:98046070-98046171 (-)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 3 alleles in 3 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    6
  • Genomic Mutations
    2 involving Mir137
  • Find Mice (IMSR)
Homozygous knockout is embryonic lethal.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 387155 NCBI Gene Model | MGI Sequence Detail 73 C57BL/6J ±  kb
transcript NR_029551 RefSeq | MGI Sequence Detail 73 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 5
    Primer pair 3
    Other 2
Other Database
Links
less
miRBase MI0000163
References
more
  • Summaries
    All 36
    Developmental Gene Expression 7
    Diseases 1
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:303499 Tian R, et al., miR-137 prevents inflammatory response, oxidative stress, neuronal injury and cognitive impairment via blockade of Src-mediated MAPK signaling pathway in ischemic stroke. Aging (Albany NY). 2020 Jun 4;12(11):10873-10895

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory