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Sytl5 Gene Detail
Summary
  • Symbol
    Sytl5
  • Name
    synaptotagmin-like 5
  • Synonyms
    ENSMUSG00000054453
Location &
Maps
more
  • Sequence Map
    ChrX:9751861-9860782 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome X, 4.62 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2124 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2668451
protein coding gene ChrX:9613851-9871268 (+)
129S1/SvImJ ENSMUSG00200032807
protein coding gene ChrX:4503195-4619793 (+)
A/J ENSMUSG00195036886
protein coding gene ChrX:4471909-4580843 (+)
AKR/J ENSMUSG00220031447
protein coding gene ChrX:4012319-4120919 (+)
BALB/cJ ENSMUSG00180029787
protein coding gene ChrX:4469660-4578570 (+)
C3H/HeJ ENSMUSG00175030286
protein coding gene ChrX:4485919-4606809 (+)
C57BL/6NJ ENSMUSG00215037006
protein coding gene ChrX:5142398-5251325 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032929
protein coding gene ChrX:3856328-3941015 (+)
CAST/EiJ ENSTCUG00005031055
protein coding gene ChrX:4471431-4576407 (+)
CBA/J ENSMUSG00210037236
protein coding gene ChrX:4534559-4649667 (+)
DBA/2J ENSMUSG00185035334
protein coding gene ChrX:11126979-11242087 (+)
FVB/NJ ENSMUSG00205024960
protein coding gene ChrX:4221642-4327963 (+)
JF1/MsJ ENSUMUG00000019840
protein coding gene ChrX:24994594-25099578 (+)
LP/J ENSMUSG00230030298
protein coding gene ChrX:15694473-15809578 (+)
NOD/ShiLtJ ENSMUSG00190029030
protein coding gene ChrX:4497085-4606008 (+)
NZO/HlLtJ ENSMUSG00225033122
protein coding gene ChrX:20912799-21027901 (+)
PWK/PhJ ENSLUMG00010029961
protein coding gene ChrX:4411924-4509739 (+)
SPRET/EiJ ENSMSPG00010022428
protein coding gene ChrX:5352325-5439978 (+)
WSB/EiJ ENSIUOG00005016465
protein coding gene ChrX:1190762-1305623 (+)



Homology
more
  • Human Ortholog
    SYTL5, synaptotagmin like 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SYTL5, synaptotagmin like 5
  • Synonyms
    slp5
  • Links
    NCBI Gene ID: 94122
    UniProt: Q8TDW5

  • Chr Location
    Xp11.4; chrX:37888915-38128820 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000054453 Ensembl Gene Model | MGI Sequence Detail 108922 C57BL/6J ±  kb
transcript ENSMUST00000067529 Ensembl | MGI Sequence Detail 2301 Not Applicable  
polypeptide ENSMUSP00000064826 Ensembl | MGI Sequence Detail 753 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
Other
Accession IDs
less
MGI:3710612
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:169802 Kuroda TS, et al., Synaptotagmin-like protein 5: a novel Rab27A effector with C-terminal tandem C2 domains. Biochem Biophys Res Commun. 2002 May 10;293(3):899-906
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory