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Zfp457 Gene Detail
Summary
  • Symbol
    Zfp457
  • Name
    zinc finger protein 457
  • Synonyms
    Rslcan-6
Location &
Maps
more
  • Sequence Map
    Chr13:67440514-67454476 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 34.54 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    432 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2664334
 protein coding gene Chr13:67436202-67454549 (-)
129S1/SvImJ ENSMUSG00200011973
 protein coding gene Chr13:62220336-62236068 (-)
A/J ENSMUSG00195027102
 protein coding gene Chr13:62474623-62490260 (-)
AKR/J ENSMUSG00220033616
 protein coding gene Chr13:61456024-61471754 (-)
BALB/cJ ENSMUSG00180023036
 protein coding gene Chr13:62954039-62969678 (-)
C3H/HeJ ENSMUSG00175007199
 protein coding gene Chr13:63265471-63281110 (-)
C57BL/6NJ ENSMUSG00215007878
 protein coding gene Chr13:62962323-62980597 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018663
 protein coding gene Chr13:62595971-62608225 (-)
CAST/EiJ ENSTCUG00005011808
 protein coding gene Chr13:62970733-62986372 (-)
CBA/J ENSMUSG00210008963
 protein coding gene Chr13:62587837-62603476 (-)
DBA/2J ENSMUSG00185008087
 protein coding gene Chr13:66283463-66299102 (-)
FVB/NJ ENSMUSG00205016214
 protein coding gene Chr13:62007817-62023453 (-)
JF1/MsJ ENSUMUG00000024387
 protein coding gene Chr13:65956282-65974556 (-)
LP/J no annotation
NOD/ShiLtJ ENSMUSG00190031262
 protein coding gene Chr13:62570141-62585779 (-)
NZO/HlLtJ no annotation
PWK/PhJ ENSLUMG00010011000
 protein coding gene Chr13:62071445-62089935 (-)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    ZNF493, zinc finger protein 493
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF493, zinc finger protein 493
  • Links
    NCBI Gene ID: 284443
    UniProt: Q6ZR52

  • Chr Location
    19p12; chr19:21397119-21427577 (+)  GRCh38
  • Human Ortholog
    ZNF600, zinc finger protein 600
  • Synonyms
    KR-ZNF1
  • Links
    NCBI Gene ID: 162966
    UniProt: Q6ZNG1

  • Chr Location
    19q13.41; chr19:52749942-52833645 (-)  GRCh38
  • Human Ortholog
    ZNF724, zinc finger protein 724
  • Synonyms
    ZNF724P
  • Links
    NCBI Gene ID: 440519
    UniProt: A8MTY0

  • Chr Location
    19p12; chr19:23221599-23250394 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 431706 NCBI Gene Model | MGI Sequence Detail 13963 C57BL/6J ±  kb
transcript NM_001003666 RefSeq | MGI Sequence Detail 2117 ZRU/MplStud  
polypeptide NP_001003666 RefSeq | MGI Sequence Detail 647 ZRU/MplStud  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR050589 Ikaros C2H2-type zinc-finger
    IPR001909 Krueppel-associated box
    IPR036051 Krueppel-associated box domain superfamily
    IPR036236 Zinc finger C2H2 superfamily
    IPR013087 Zinc finger C2H2-type
    IPR050758 Zinc finger protein, C2H2-type
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 18
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:86324 Krebs CJ, et al., Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression. Genes Dev. 2003 Nov 1;17(21):2664-74
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory