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Zc3h3 Gene Detail
Summary
  • Symbol
    Zc3h3
  • Name
    zinc finger CCCH type containing 3
  • Synonyms
    Smicl
  • Feature Type
    protein coding gene
  • IDs
    MGI:2663721
    NCBI Gene: 223642
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:75626279-75713764 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 34.84 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    305 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2663721
 protein coding gene Chr15:75626279-75713772 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021959
 protein coding gene Chr15:75784114-75877848 (-)
A/J MGP_AJ_G0021917
 protein coding gene Chr15:73036184-73123981 (-)
AKR/J MGP_AKRJ_G0021900
 protein coding gene Chr15:75000503-75089295 (-)
BALB/cJ MGP_BALBcJ_G0021926
 protein coding gene Chr15:73049467-73138930 (-)
C3H/HeJ MGP_C3HHeJ_G0021698
 protein coding gene Chr15:75067850-75160117 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022366
 protein coding gene Chr15:78618234-78712911 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019897
 protein coding gene Chr15:69711924-69798332 (-)
CAST/EiJ MGP_CASTEiJ_G0021217
 protein coding gene Chr15:75849784-75936831 (-)
CBA/J MGP_CBAJ_G0021665
 protein coding gene Chr15:81142769-81231284 (-)
DBA/2J MGP_DBA2J_G0021790
 protein coding gene Chr15:72550423-72651484 (-)
FVB/NJ MGP_FVBNJ_G0021771
 protein coding gene Chr15:71610963-71702392 (-)
LP/J MGP_LPJ_G0021861
 protein coding gene Chr15:75878720-75968754 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021795
 protein coding gene Chr15:86445439-86540629 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022386
 protein coding gene Chr15:75253762-75344736 (-)
PWK/PhJ MGP_PWKPhJ_G0020958
 protein coding gene Chr15:72692855-72781486 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020797
 protein coding gene Chr15:74983421-75071074 (-)
WSB/EiJ MGP_WSBEiJ_G0021269
 protein coding gene Chr15:75336944-75428405 (-)



Homology
more
  • Human Ortholog
    ZC3H3, zinc finger CCCH-type containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZC3H3, zinc finger CCCH-type containing 3
  • Synonyms
    SMICL, ZC3HDC3
  • Links
    NCBI Gene ID: 23144
    neXtProt AC: NX_Q8IXZ2
    UniProt: Q8IXZ2

  • Chr Location
    8q24.3; chr8:143437659-143541447 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    31 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    759
  • Tissues
    32
  • cDNA Data
    42
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000075600 Ensembl Gene Model | MGI Sequence Detail 87486 C57BL/6J ±  kb
transcript ENSMUST00000100538 Ensembl | MGI Sequence Detail 3362 Not Applicable  
polypeptide ENSMUSP00000098106 Ensembl | MGI Sequence Detail 950 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 42
    cDNA 42

    Microarray probesets 4
References
more
  • Summaries
    All 59
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 6
    Phenotypes 31
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory