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Prl3d3 Gene Detail
Summary
  • Symbol
    Prl3d3
  • Name
    prolactin family 3, subfamily d, member 3
  • Synonyms
    Plig, PL-Ig
  • Feature Type
    protein coding gene
  • IDs
    MGI:2660938
    NCBI Gene: 215029
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr13:27340777-27346576 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 12.30 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    4 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2660938
 protein coding gene Chr13:27340773-27346576 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0020342
 protein coding gene Chr13:24187112-24190703 (+)
AKR/J MGP_AKRJ_G0020322
 protein coding gene Chr13:24547249-24554482 (+)
BALB/cJ MGP_BALBcJ_G0020340
 protein coding gene Chr13:24208725-24215487 (+)
C3H/HeJ MGP_C3HHeJ_G0020142
 protein coding gene Chr13:24539438-24659193 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020776
 protein coding gene Chr13:25643165-25648287 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0019661
 protein coding gene Chr13:24286656-24343611 (+)
CBA/J MGP_CBAJ_G0020096
 protein coding gene Chr13:26553781-26590545 (+)
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0020296
 protein coding gene Chr13:24962748-25009971 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020234
 protein coding gene Chr13:26880428-26885256 (+)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0019415
 protein coding gene Chr13:23690578-23697144 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019231
 protein coding gene Chr13:23215847-23221830 (+)
WSB/EiJ MGP_WSBEiJ_G0019720
 protein coding gene Chr13:24520996-24526846 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Prl3d3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    17 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    733
  • Tissues
    13
  • cDNA Data
    7
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 215029 NCBI Gene Model | MGI Sequence Detail 5800 C57BL/6J ±  kb
transcript NM_001361097 RefSeq | MGI Sequence Detail 868 C57BL/6  
polypeptide NP_001348026 RefSeq | MGI Sequence Detail 224 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR009079 Four-helical cytokine-like, core
    IPR018116 Somatotropin hormone, conserved site
    IPR001400 Somatotropin/prolactin
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 1
References
more
  • Summaries
    All 27
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:314901 Bao H, et al., Hyperactivated Wnt-beta-catenin signaling in the absence of sFRP1 and sFRP5 disrupts trophoblast differentiation through repression of Ascl2. BMC Biol. 2020 Oct 27;18(1):151
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory