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Gucy1a2 Gene Detail
Summary
  • Symbol
    Gucy1a2
  • Name
    guanylate cyclase 1, soluble, alpha 2
  • Synonyms
    6330407I18Rik, A230060L24Rik
Location &
Maps
more
  • Sequence Map
    Chr9:3532778-3894736 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 2.14 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    8171 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2660877
 protein coding gene Chr9:3532349-3905791 (+)
129S1/SvImJ ENSMUSG00200022811
 protein coding gene Chr9:364323-726718 (+)
A/J ENSMUSG00195017601
 protein coding gene Chr9:291418-653792 (+)
AKR/J ENSMUSG00220018516
 protein coding gene Chr9:400912-763620 (+)
BALB/cJ ENSMUSG00180011313
 protein coding gene Chr9:432065-794451 (+)
C3H/HeJ ENSMUSG00175022980
 protein coding gene Chr9:354140-716521 (+)
C57BL/6NJ ENSMUSG00215005736
 protein coding gene Chr9:367905-730293 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031738
 protein coding gene Chr9:151317-422242 (+)
CAST/EiJ ENSTCUG00005007106
 protein coding gene Chr9:451087-810389 (+)
CBA/J ENSMUSG00210010523
 protein coding gene Chr9:315593-680999 (+)
DBA/2J ENSMUSG00185005040
 protein coding gene Chr9:500076-862453 (+)
FVB/NJ ENSMUSG00205006786
 protein coding gene Chr9:481218-841792 (+)
JF1/MsJ ENSUMUG00000007808
 protein coding gene Chr9:483153-844168 (+)
LP/J ENSMUSG00230003168
 protein coding gene Chr9:953499-1325000 (+)
NOD/ShiLtJ ENSMUSG00190021192
 protein coding gene Chr9:392956-761909 (+)
NZO/HlLtJ ENSMUSG00225016194
 protein coding gene Chr9:832220-1194587 (+)
PWK/PhJ ENSLUMG00010006406
 protein coding gene Chr9:461412-823394 (+)
SPRET/EiJ ENSMSPG00010005432
 protein coding gene Chr9:427877-799577 (+)
WSB/EiJ ENSIUOG00005007290
 protein coding gene Chr9:284399-653306 (+)



Homology
more
  • Human Ortholog
    GUCY1A2, guanylate cyclase 1 soluble subunit alpha 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GUCY1A2, guanylate cyclase 1 soluble subunit alpha 2
  • Synonyms
    GC-SA2, GUC1A2
  • Links
    NCBI Gene ID: 2977
    UniProt: P33402

  • Chr Location
    11q22.3; chr11:106674019-107018476 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Mice homozygous for a null mutation display normal blood vessel and platelet physiology.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    693
  • Tissues
    96
  • cDNA Data
    19
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041624 Ensembl Gene Model | MGI Sequence Detail 361959 C57BL/6J ±  kb
transcript ENSMUST00000115733 Ensembl | MGI Sequence Detail 2243 Not Applicable  
polypeptide ENSMUSP00000111398 Ensembl | MGI Sequence Detail 730 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 21
    cDNA 19
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:1917960, MGI:2444229
References
more
  • Summaries
    All 45
    Developmental Gene Expression 2
    Gene Ontology 11
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory