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Aldh8a1 Gene Detail
Summary
  • Symbol
    Aldh8a1
  • Name
    aldehyde dehydrogenase 8 family, member A1
  • Synonyms
    RALDH4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2653900
    NCBI Gene: 237320
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:21253199-21272477 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 9.75 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    688 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2653900
 protein coding gene Chr10:21253190-21272484 (+)
129S1/SvImJ ENSMUSG00200010206
 protein coding gene Chr10:18242468-18261836 (+)
A/J ENSMUSG00195006765
 protein coding gene Chr10:18254590-18273967 (+)
AKR/J ENSMUSG00220009996
 protein coding gene Chr10:18166060-18185359 (+)
BALB/cJ ENSMUSG00180014695
 protein coding gene Chr10:18378838-18398208 (+)
C3H/HeJ ENSMUSG00175020128
 protein coding gene Chr10:18401324-18420619 (+)
C57BL/6NJ ENSMUSG00215003565
 protein coding gene Chr10:18208444-18227742 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015164
 protein coding gene Chr10:17409407-17429002 (+)
CAST/EiJ ENSTCUG00005027745
 protein coding gene Chr10:18167406-18186836 (+)
CBA/J ENSMUSG00210015445
 protein coding gene Chr10:18338430-18357723 (+)
DBA/2J ENSMUSG00185006731
 protein coding gene Chr10:18323432-18342725 (+)
FVB/NJ ENSMUSG00205015337
 protein coding gene Chr10:18235751-18255123 (+)
JF1/MsJ ENSUMUG00000008139
 protein coding gene Chr10:18377775-18397209 (+)
LP/J ENSMUSG00230014931
 protein coding gene Chr10:19976490-19995858 (+)
NOD/ShiLtJ ENSMUSG00190010322
 protein coding gene Chr10:18313708-18333076 (+)
NZO/HlLtJ ENSMUSG00225030083
 protein coding gene Chr10:24464104-24483429 (+)
PWK/PhJ ENSLUMG00010015238
 protein coding gene Chr10:18146290-18165597 (+)
SPRET/EiJ ENSMSPG00010010799
 protein coding gene Chr10:18781351-18800502 (+)
WSB/EiJ ENSIUOG00005021468
 protein coding gene Chr10:17945082-17964380 (+)



Homology
more
  • Human Ortholog
    ALDH8A1, aldehyde dehydrogenase 8 family member A1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ALDH8A1, aldehyde dehydrogenase 8 family member A1
  • Synonyms
    ALDH12, DJ352A20.2
  • Links
    NCBI Gene ID: 64577
    UniProt: Q9H2A2

  • Chr Location
    6q23.3; chr6:134917298-134950129 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    642
  • Tissues
    14
  • cDNA Data
    31
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 237320 NCBI Gene Model | MGI Sequence Detail 19279 C57BL/6J ±  kb
transcript NM_178713 RefSeq | MGI Sequence Detail 2243 C57BL/6  
polypeptide Q8BH00 UniProt | EBI | MGI Sequence Detail 487 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 35
    cDNA 31
    Primer pair 2
    Other 2

    Microarray probesets 4
References
more
  • Summaries
    All 48
    Developmental Gene Expression 7
    Gene Ontology 11
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:273031 Teletin M, et al., Two functionally redundant sources of retinoic acid secure spermatogonia differentiation in the seminiferous epithelium. Development. 2019 Jan 4;146(1):dev170225
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory