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Zfp950 Gene Detail
Summary
  • Symbol
    Zfp950
  • Name
    zinc finger protein 950
  • Synonyms
    5830428H23Rik, 5830428H23Rik, BC029127, Gm34518, Zfp826
  • Feature Type
    protein coding gene
  • IDs
    MGI:2652824
    NCBI Gene: 414758
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:61042692-61129297 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 19, 56.67 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    579 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2652824
protein coding gene Chr19:61042278-61129297 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025300
protein coding gene Chr19:61660234-61748601 (-)
A/J MGP_AJ_G0025276
protein coding gene Chr19:58656376-58748298 (-)
AKR/J MGP_AKRJ_G0025245
protein coding gene Chr19:60487566-60579872 (-)
BALB/cJ MGP_BALBcJ_G0025271
protein coding gene Chr19:58734206-58825381 (-)
C3H/HeJ MGP_C3HHeJ_G0025031
protein coding gene Chr19:60728494-60821378 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025714
protein coding gene Chr19:63121099-63211286 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023126
protein coding gene Chr19:57475317-57559292 (-)
CAST/EiJ MGP_CASTEiJ_G0024496
protein coding gene Chr19:60839411-60930405 (-)
CBA/J MGP_CBAJ_G0025011
protein coding gene Chr19:66196241-66305142 (-)
DBA/2J MGP_DBA2J_G0025143
protein coding gene Chr19:58436569-58524531 (-)
FVB/NJ MGP_FVBNJ_G0025104
protein coding gene Chr19:58103544-58196021 (-)
LP/J MGP_LPJ_G0025229
protein coding gene Chr19:61489377-61575970 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025137
protein coding gene Chr19:65386149-65488940 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025772
protein coding gene Chr19:60726123-60827061 (-)
PWK/PhJ MGP_PWKPhJ_G0024244
protein coding gene Chr19:58381652-58471752 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024047
protein coding gene Chr19:59395432-59487410 (-)
WSB/EiJ MGP_WSBEiJ_G0024566
protein coding gene Chr19:60835791-60931672 (-)



Homology
more
  • Human Ortholog
    ZNF234, zinc finger protein 234
  • Vertebrate Orthologs
    15
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF234, zinc finger protein 234
  • Synonyms
    HZF4, ZNF269
  • Links
    NCBI Gene ID: 10780
    neXtProt AC: NX_Q14588
    UniProt: Q14588

  • Chr Location
    19q13.31; chr19:44141554-44160313 (+)  GRCh38

  • Human Ortholog
    ZNF254, zinc finger protein 254
  • Synonyms
    BMZF-5, HD-ZNF1, ZNF539, ZNF91L
  • Links
    NCBI Gene ID: 9534
    neXtProt AC: NX_O75437
    UniProt: O75437

  • Chr Location
    19p12; chr19:24033405-24129968 (+)  GRCh38

  • Human Ortholog
    ZNF28, zinc finger protein 28
  • Synonyms
    KOX24
  • Links
    NCBI Gene ID: 7576
    neXtProt AC: NX_P17035
    UniProt: P17035

  • Chr Location
    19q13.41; chr19:52797408-52857600 (-)  GRCh38

  • Human Ortholog
    ZNF432, zinc finger protein 432
  • Links
    NCBI Gene ID: 9668
    neXtProt AC: NX_O94892
    UniProt: O94892

  • Chr Location
    19q13.41; chr19:52031378-52095738 (-)  GRCh38

  • Human Ortholog
    ZNF493, zinc finger protein 493
  • Links
    NCBI Gene ID: 284443
    neXtProt AC: NX_Q6ZR52
    UniProt: Q6ZR52

  • Chr Location
    19p12; chr19:21397119-21427577 (+)  GRCh38

  • Human Ortholog
    ZNF595, zinc finger protein 595
  • Links
    NCBI Gene ID: 152687
    neXtProt AC: NX_Q8IYB9
    UniProt: Q8IYB9

  • Chr Location
    4p16.3; chr4:53286-88208 (+)  GRCh38

  • Human Ortholog
    ZNF611, zinc finger protein 611
  • Links
    NCBI Gene ID: 81856
    neXtProt AC: NX_Q8N823
    UniProt: Q8N823

  • Chr Location
    19q13.41; chr19:52702813-52735073 (-)  GRCh38

  • Human Ortholog
    ZNF615, zinc finger protein 615
  • Links
    NCBI Gene ID: 284370
    neXtProt AC: NX_Q8N8J6
    UniProt: Q8N8J6

  • Chr Location
    19q13.41; chr19:51991332-52008230 (-)  GRCh38

  • Human Ortholog
    ZNF676, zinc finger protein 676
  • Links
    NCBI Gene ID: 163223
    neXtProt AC: NX_Q8N7Q3
    UniProt: Q8N7Q3

  • Chr Location
    19p12; chr19:22179089-22260304 (-)  GRCh38

  • Human Ortholog
    ZNF726, zinc finger protein 726
  • Synonyms
    ZNF92P3
  • Links
    NCBI Gene ID: 730087
    neXtProt AC: NX_A6NNF4
    UniProt: A6NNF4

  • Chr Location
    19p12; chr19:23914876-23945159 (+)  GRCh38

  • Human Ortholog
    ZNF728, zinc finger protein 728
  • Links
    NCBI Gene ID: 388523
    neXtProt AC: NX_P0DKX0
    UniProt: P0DKX0

  • Chr Location
    19p12; chr19:22974883-23003176 (-)  GRCh38

  • Human Ortholog
    ZNF732, zinc finger protein 732
  • Links
    NCBI Gene ID: 654254
    neXtProt AC: NX_B4DXR9
    UniProt: B4DXR9

  • Chr Location
    4p16.3; chr4:270675-305474 (-)  GRCh38

  • Human Ortholog
    ZNF93, zinc finger protein 93
  • Synonyms
    HPF34, HTF34, TF34, ZNF505
  • Links
    NCBI Gene ID: 81931
    neXtProt AC: NX_P35789
    UniProt: P35789

  • Chr Location
    19p12; chr19:19900913-19963464 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    27 phenotypes from 1 allele in 1 genetic background
    10 phenotypes from multigenic genotypes
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trapped allele exhibit some postnatal lethality, altered craniofacial structures, kidney defects, embryonic hemorrhaging and cell migration defects.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 414758 NCBI Gene Model | MGI Sequence Detail 86606 C57BL/6J ±  kb
    transcript NM_001409028 RefSeq | MGI Sequence Detail 3443 C57BL/6  
    polypeptide NP_001296145 RefSeq | MGI Sequence Detail 609 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 20
      cDNA 20

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1926073, MGI:3034944, MGI:3042551, MGI:5593677
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 4
      Gene Ontology 3
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    04/09/2024
    MGI 6.23
    The Jackson Laboratory