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Rasef Gene Detail
Summary
  • Symbol
    Rasef
  • Name
    RAS and EF hand domain containing
  • Synonyms
    RAB45
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448565
    NCBI Gene: 242505
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:73632816-73709231 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 36.06 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1953 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448565
 protein coding gene Chr4:73632814-73709382 (-)
129S1/SvImJ ENSMUSG00200000472
 protein coding gene Chr4:68577139-68653631 (-)
A/J ENSMUSG00195000872
 protein coding gene Chr4:69114095-69190539 (-)
AKR/J ENSMUSG00220018445
 protein coding gene Chr4:68840335-68916764 (-)
BALB/cJ ENSMUSG00180000804
 protein coding gene Chr4:68080138-68156572 (-)
C3H/HeJ ENSMUSG00175006467
 protein coding gene Chr4:69016234-69092658 (-)
C57BL/6NJ ENSMUSG00215000785
 protein coding gene Chr4:69008202-69084627 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026109
 protein coding gene Chr4:66973777-67045883 (-)
CAST/EiJ ENSTCUG00005014268
 protein coding gene Chr4:68641931-68718417 (-)
CBA/J ENSMUSG00210000487
 protein coding gene Chr4:68618583-68695020 (-)
DBA/2J ENSMUSG00185015150
 protein coding gene Chr4:69174088-69250570 (-)
FVB/NJ ENSMUSG00205000911
 protein coding gene Chr4:67356039-67432472 (-)
JF1/MsJ ENSUMUG00000000518
 protein coding gene Chr4:69780076-69859130 (-)
LP/J ENSMUSG00230008134
 protein coding gene Chr4:72669758-72746241 (-)
NOD/ShiLtJ ENSMUSG00190009044
 protein coding gene Chr4:68026711-68103141 (-)
NZO/HlLtJ ENSMUSG00225027884
 protein coding gene Chr4:77686943-77763364 (-)
PWK/PhJ ENSLUMG00010009477
 protein coding gene Chr4:67521748-67598800 (-)
SPRET/EiJ ENSMSPG00010004918
 protein coding gene Chr4:68878350-68951050 (-)
WSB/EiJ ENSIUOG00005000306
 protein coding gene Chr4:68417830-68494216 (-)



Homology
more
  • Human Ortholog
    RASEF, RAS and EF-hand domain containing
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RASEF, RAS and EF-hand domain containing
  • Synonyms
    RAB45, TSG
  • Links
    NCBI Gene ID: 158158
    UniProt: Q8IZ41

  • Chr Location
    9q21.32; chr9:82979590-83219224 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Males homozygous for a null allele show normal male fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    37
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000043003 Ensembl Gene Model | MGI Sequence Detail 76416 C57BL/6J ±  kb
transcript ENSMUST00000222414 Ensembl | MGI Sequence Detail 2127 Not Applicable  
polypeptide ENSMUSP00000152127 Ensembl | MGI Sequence Detail 708 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 3
References
more
  • Summaries
    All 36
    Gene Ontology 8
    Phenotypes 10
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:360422 Sato K, et al., RASEF/Rab45 regulates the formation and sorting of zymogen granules and secretion of digestive enzymes by pancreatic acinar cells. Biochim Biophys Acta Mol Basis Dis. 2024 Jun 18;1870(7):167310
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory