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Zfp637 Gene Detail
Summary
  • Symbol
    Zfp637
  • Name
    zinc finger protein 637
  • Synonyms
    MGC:54806
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448537
    NCBI Gene: 232337
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:117818165-117822917 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 6, 55.59 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    238 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448537
protein coding gene Chr6:117818141-117822917 (+)
129S1/SvImJ ENSMUSG00200050603
protein coding gene Chr6:115025916-115035305 (+)
A/J ENSMUSG00195047373
protein coding gene Chr6:114426081-114435472 (+)
AKR/J ENSMUSG00220026557
protein coding gene Chr6:113311973-113321362 (+)
BALB/cJ ENSMUSG00180046990
protein coding gene Chr6:114793785-114803195 (+)
C3H/HeJ ENSMUSG00175033238
protein coding gene Chr6:62666884-62676338 (-)
C57BL/6NJ ENSMUSG00215046300
protein coding gene Chr6:114783975-114793364 (+)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005047623
protein coding gene Chr6:114581815-114592490 (+)
CBA/J ENSMUSG00210033157
protein coding gene Chr6:114561106-114570495 (+)
DBA/2J ENSMUSG00185044310
protein coding gene Chr6:115219381-115228770 (+)
FVB/NJ ENSMUSG00205025895
protein coding gene Chr6:113676191-113686394 (+)
JF1/MsJ ENSUMUG00000051954
protein coding gene Chr6:113816280-113826453 (+)
LP/J ENSMUSG00230042840
protein coding gene Chr6:116423464-116432853 (+)
NOD/ShiLtJ ENSMUSG00190045563
protein coding gene Chr6:114173381-114182770 (+)
NZO/HlLtJ ENSMUSG00225044941
protein coding gene Chr6:118279289-118288678 (+)
PWK/PhJ ENSLUMG00010038624
protein coding gene Chr6:113175201-113185399 (+)
SPRET/EiJ ENSMSPG00010037290
protein coding gene Chr6:116018307-116022971 (+)
WSB/EiJ ENSIUOG00005043094
protein coding gene Chr6:114851620-114861504 (+)



Homology
more
  • Human Ortholog
    ZNF32, zinc finger protein 32
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF32, zinc finger protein 32
  • Synonyms
    KOX30, Zfp637, ZNF637
  • Links
    NCBI Gene ID: 7580
    UniProt: P17041

  • Chr Location
    10q11.21; chr10:43643859-43649367 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele do not display any obvious phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 232337 NCBI Gene Model | MGI Sequence Detail 4753 C57BL/6J ±  kb
    transcript NM_001411614 RefSeq | MGI Sequence Detail 1522 C57BL/6  
    polypeptide Q80V23 UniProt | EBI | MGI Sequence Detail 272 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 54
      cDNA 54

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2141459
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 12
    • Earliest
      J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    09/08/2026
    MGI 6.24
    The Jackson Laboratory