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Fam13b Gene Detail
Summary
  • Symbol
    Fam13b
  • Name
    family with sequence similarity 13, member B
  • Synonyms
    2610024E20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2447834
    NCBI Gene: 225358
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:34575404-34639884 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 18.69 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1557 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2447834
 protein coding gene Chr18:34573624-34656096 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024240
 protein coding gene Chr18:32648452-32716823 (-)
A/J MGP_AJ_G0024206
 protein coding gene Chr18:31553922-31621090 (-)
AKR/J MGP_AKRJ_G0024175
 protein coding gene Chr18:32448774-32517299 (-)
BALB/cJ MGP_BALBcJ_G0024206
 protein coding gene Chr18:31615054-31679607 (-)
C3H/HeJ MGP_C3HHeJ_G0023974
 protein coding gene Chr18:32466028-32534233 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024648
 protein coding gene Chr18:33887574-33963252 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022089
 protein coding gene Chr18:31695023-31758729 (-)
CAST/EiJ MGP_CASTEiJ_G0023449
 protein coding gene Chr18:32405635-32476092 (-)
CBA/J MGP_CBAJ_G0023942
 protein coding gene Chr18:34833468-34911116 (-)
DBA/2J MGP_DBA2J_G0024074
 protein coding gene Chr18:31214167-31278612 (-)
FVB/NJ MGP_FVBNJ_G0024040
 protein coding gene Chr18:30898263-30962487 (-)
LP/J MGP_LPJ_G0024155
 protein coding gene Chr18:32736511-32803195 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024068
 protein coding gene Chr18:36111049-36182401 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024696
 protein coding gene Chr18:32275602-32341017 (-)
PWK/PhJ MGP_PWKPhJ_G0023192
 protein coding gene Chr18:31398101-31463713 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023001
 protein coding gene Chr18:32536523-32606841 (-)
WSB/EiJ MGP_WSBEiJ_G0023512
 protein coding gene Chr18:32196432-32262540 (-)



Homology
more
  • Human Ortholog
    FAM13B, family with sequence similarity 13 member B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM13B, family with sequence similarity 13 member B
  • Synonyms
    ARHGAP49, C5orf5, FAM13B1, KHCHP, N61
  • Links
    NCBI Gene ID: 51306
    UniProt: Q9NYF5

  • Chr Location
    5q31.2; chr5:137937960-138052178 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 2 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit normal heart size and do not develop spontaneous arrhythmia but show increased P-wave duration and QT interval and increased susceptibility to pacing-induced atrial and ventricular arrhythmias.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    769
  • Tissues
    37
  • cDNA Data
    6
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000036501 Ensembl Gene Model | MGI Sequence Detail 64481 C57BL/6J ±  kb
    transcript ENSMUST00000040506 Ensembl | MGI Sequence Detail 3344 Not Applicable  
    polypeptide ENSMUSP00000038199 Ensembl | MGI Sequence Detail 851 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2147343, MGI:2147371
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 1
      Phenotypes 14
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory