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Adh6b Gene Detail
Summary
  • Symbol
    Adh6b
  • Name
    alcohol dehydrogenase 6B (class V)
  • Synonyms
    Adh5b
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446626
    NCBI Gene: 100417514
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:138047536-138064622 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 64.21 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    236 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446626
 protein coding gene Chr3:138047176-138064622 (+)
129S1/SvImJ MGP_129S1SvImJ_G0039823
 pseudogene Chr3:141395174-141412005 (+)
A/J MGP_AJ_G0039824
 pseudogene Chr3:136384474-136401430 (+)
AKR/J MGP_AKRJ_G0039750
 pseudogene Chr3:140014955-140031879 (+)
BALB/cJ MGP_BALBcJ_G0039795
 pseudogene Chr3:136190439-136207266 (+)
C3H/HeJ MGP_C3HHeJ_G0039450
 pseudogene Chr3:140337137-140353922 (+)
C57BL/6NJ MGP_C57BL6NJ_G0040363
 pseudogene Chr3:146267728-146284597 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0036970
 pseudogene Chr3:131800323-131818217 (+)
CAST/EiJ MGP_CASTEiJ_G0038561
 pseudogene Chr3:140112082-140129023 (+)
CBA/J MGP_CBAJ_G0039420
 pseudogene Chr3:151228676-151245421 (+)
DBA/2J MGP_DBA2J_G0039621
 pseudogene Chr3:135504784-135521605 (+)
FVB/NJ MGP_FVBNJ_G0039578
 pseudogene Chr3:132964519-132981455 (+)
LP/J MGP_LPJ_G0039657
 pseudogene Chr3:142779987-142796816 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0039578
 pseudogene Chr3:159324029-159340960 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0040466
 pseudogene Chr3:139557364-139574123 (+)
PWK/PhJ MGP_PWKPhJ_G0038241
 pseudogene Chr3:135268679-135285750 (+)
SPRET/EiJ MGP_SPRETEiJ_G0037985
 pseudogene Chr3:137657953-137675509 (+)
WSB/EiJ MGP_WSBEiJ_G0038796
 pseudogene Chr3:140397414-140414511 (+)



Homology
more
  • Human Ortholog
    ADH6, alcohol dehydrogenase 6 (class V)
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ADH6, alcohol dehydrogenase 6 (class V)
  • Synonyms
    ADH-5
  • Links
    NCBI Gene ID: 130
    neXtProt AC: NX_P28332
    UniProt: P28332

  • Chr Location
    4q23; chr4:99202638-99219537 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074206 Ensembl Gene Model | MGI Sequence Detail 17087 C57BL/6J ±  kb
transcript ENSMUST00000199673 Ensembl | MGI Sequence Detail 1700 Not Applicable  
polypeptide ENSMUSP00000148703 Ensembl | MGI Sequence Detail 384 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR013149 Alcohol dehydrogenase-like, C-terminal
    IPR013154 Alcohol dehydrogenase-like, N-terminal
    IPR002328 Alcohol dehydrogenase, zinc-type, conserved site
    IPR011032 GroES-like superfamily
    IPR036291 NAD(P)-binding domain superfamily
    IPR020843 Polyketide synthase, enoylreductase domain
Molecular
Reagents
less
  • All nucleic 5
    Genomic 1
    cDNA 4

    Microarray probesets 1
References
more
  • Summaries
    All 20
    Diseases 1
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory