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Arrdc1 Gene Detail
Summary
  • Symbol
    Arrdc1
  • Name
    arrestin domain containing 1
  • Synonyms
    MGC:28029
  • Feature Type
    protein coding gene
  • IDs
    MGI:2446136
    NCBI Gene: 215705
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:24815364-24825264 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 16.84 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    83 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2446136
 protein coding gene Chr2:24815364-24825347 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025413
 protein coding gene Chr2:22767246-22776641 (-)
A/J MGP_AJ_G0025390
 protein coding gene Chr2:21880226-21889861 (-)
AKR/J MGP_AKRJ_G0025360
 protein coding gene Chr2:22633625-22643592 (-)
BALB/cJ MGP_BALBcJ_G0025386
 protein coding gene Chr2:22000971-22013658 (-)
C3H/HeJ MGP_C3HHeJ_G0025147
 protein coding gene Chr2:22554006-22565531 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025830
 protein coding gene Chr2:23494236-23504313 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023241
 protein coding gene Chr2:20817220-20826548 (-)
CAST/EiJ MGP_CASTEiJ_G0024610
 protein coding gene Chr2:22443242-22454587 (-)
CBA/J MGP_CBAJ_G0025125
 protein coding gene Chr2:24303242-24312605 (-)
DBA/2J MGP_DBA2J_G0025258
 protein coding gene Chr2:21742819-21751916 (-)
FVB/NJ MGP_FVBNJ_G0025220
 protein coding gene Chr2:21481223-21490858 (-)
LP/J MGP_LPJ_G0025344
 protein coding gene Chr2:22713237-22723605 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025251
 protein coding gene Chr2:24524613-24536337 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025889
 protein coding gene Chr2:22565777-22575092 (-)
PWK/PhJ MGP_PWKPhJ_G0024358
 protein coding gene Chr2:21541586-21553385 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024158
 protein coding gene Chr2:22711969-22721612 (-)
WSB/EiJ MGP_WSBEiJ_G0024679
 protein coding gene Chr2:22645201-22655468 (-)



Homology
more
  • Human Ortholog
    ARRDC1, arrestin domain containing 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARRDC1, arrestin domain containing 1
  • Links
    NCBI Gene ID: 92714
    neXtProt AC: NX_Q8N5I2
    UniProt: Q8N5I2

  • Chr Location
    9q34.3; chr9:137605685-137615360 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mouse embryonic fibroblasts exhibit reduced extracellular vesicle release.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    797
  • Tissues
    27
  • cDNA Data
    87
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000026972 Ensembl Gene Model | MGI Sequence Detail 9901 C57BL/6J ±  kb
    transcript ENSMUST00000028349 Ensembl | MGI Sequence Detail 1666 Not Applicable  
    polypeptide ENSMUSP00000028349 Ensembl | MGI Sequence Detail 434 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 87
      cDNA 87

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:2139117
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 3
      Gene Ontology 5
      Phenotypes 10
    • Earliest
      J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
    • Latest
      J:304253 Jones MR, et al., A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis. Front Genet. 2018;9:746
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory