About   Help   FAQ
Zfp438 Gene Detail
Summary
  • Symbol
    Zfp438
  • Name
    zinc finger protein 438
  • Synonyms
    9430091M14Rik, B830013J05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444919
    NCBI Gene: 240186
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:5210029-5334807 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 3.02 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2686 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444919
 protein coding gene Chr18:5210027-5334826 (-)
129S1/SvImJ ENSMUSG00200024319
 protein coding gene Chr18:2126582-2253870 (-)
A/J ENSMUSG00195008345
 protein coding gene Chr18:2321911-2446705 (-)
AKR/J ENSMUSG00220018555
 protein coding gene Chr18:2315313-2442604 (-)
BALB/cJ ENSMUSG00180005240
 protein coding gene Chr18:2790675-2915489 (-)
C3H/HeJ ENSMUSG00175007051
 protein coding gene Chr18:2326196-2451002 (-)
C57BL/6NJ ENSMUSG00215012457
 protein coding gene Chr18:2042750-2167536 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021972
 protein coding gene Chr18:1879469-1995764 (-)
CAST/EiJ ENSTCUG00005016390
 protein coding gene Chr18:2278275-2405364 (-)
CBA/J ENSMUSG00210021724
 protein coding gene Chr18:2333057-2457867 (-)
DBA/2J ENSMUSG00185029790
 protein coding gene Chr18:2321724-2446512 (-)
FVB/NJ ENSMUSG00205028831
 protein coding gene Chr18:2077229-2202026 (-)
JF1/MsJ ENSUMUG00000029875
 protein coding gene Chr18:2337494-2464986 (-)
LP/J ENSMUSG00230025532
 protein coding gene Chr18:4375928-4503210 (-)
NOD/ShiLtJ ENSMUSG00190009845
 protein coding gene Chr18:2084299-2209085 (-)
NZO/HlLtJ ENSMUSG00225033515
 protein coding gene Chr18:4304915-4429695 (-)
PWK/PhJ ENSLUMG00010008665
 protein coding gene Chr18:2512376-2639713 (-)
SPRET/EiJ ENSMSPG00010011249
 protein coding gene Chr18:2026637-2164716 (-)
WSB/EiJ ENSIUOG00005025590
 protein coding gene Chr18:2236531-2363821 (-)



Homology
more
  • Human Ortholog
    ZNF438, zinc finger protein 438
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF438, zinc finger protein 438
  • Synonyms
    bA330O11.1
  • Links
    NCBI Gene ID: 220929
    UniProt: Q7Z4V0

  • Chr Location
    10p11.23; chr10:30820207-31032411 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    630
  • Tissues
    24
  • cDNA Data
    19
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050945 Ensembl Gene Model | MGI Sequence Detail 124779 C57BL/6J ±  kb
transcript ENSMUST00000063989 Ensembl | MGI Sequence Detail 3211 Not Applicable  
polypeptide ENSMUSP00000067049 Ensembl | MGI Sequence Detail 798 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR036236 Zinc finger C2H2 superfamily
    IPR013087 Zinc finger C2H2-type
Molecular
Reagents
less
  • All nucleic 20
    cDNA 19
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:1924617
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory