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L3mbtl4 Gene Detail
Summary
  • Symbol
    L3mbtl4
  • Name
    L3MBTL4 histone methyl-lysine binding protein
  • Synonyms
    A730037L19Rik, D930040M24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444889
    NCBI Gene: 320858
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:68580792-69087081 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 39.30 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    15581 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444889
 protein coding gene Chr17:68579893-69091073 (+)
129S1/SvImJ ENSMUSG00200038300
 protein coding gene Chr17:63937805-64435140 (+)
A/J ENSMUSG00195017620
 protein coding gene Chr17:65273759-65776069 (+)
AKR/J ENSMUSG00220017256
 protein coding gene Chr17:64346524-64848839 (+)
BALB/cJ ENSMUSG00180018107
 protein coding gene Chr17:65011053-65513396 (+)
C3H/HeJ ENSMUSG00175028117
 protein coding gene Chr17:64322599-64827607 (+)
C57BL/6NJ ENSMUSG00215017310
 protein coding gene Chr17:63972798-64480562 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021845
 protein coding gene Chr17:64379376-64843262 (+)
CAST/EiJ ENSTCUG00005025223
 protein coding gene Chr17:64902309-65401861 (+)
CBA/J ENSMUSG00210026704
 protein coding gene Chr17:64122447-64627418 (+)
DBA/2J ENSMUSG00185022039
 protein coding gene Chr17:66966167-67471254 (+)
FVB/NJ ENSMUSG00205012706
 protein coding gene Chr17:64751792-65254159 (+)
JF1/MsJ ENSUMUG00000037853
 protein coding gene Chr17:66632232-67135907 (+)
LP/J ENSMUSG00230013022
 protein coding gene Chr17:67955950-68453276 (+)
NOD/ShiLtJ ENSMUSG00190030925
 protein coding gene Chr17:64102065-64610567 (+)
NZO/HlLtJ ENSMUSG00225025977
 protein coding gene Chr17:70228657-70730901 (+)
PWK/PhJ ENSLUMG00010028669
 protein coding gene Chr17:63904858-64404778 (+)
SPRET/EiJ ENSMSPG00010015133
 protein coding gene Chr17:64315093-64772741 (+)
WSB/EiJ ENSIUOG00005031582
 protein coding gene Chr17:64991709-65488469 (+)



Homology
more
  • Human Ortholog
    L3MBTL4, L3MBTL histone methyl-lysine binding protein 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    L3MBTL4, L3MBTL histone methyl-lysine binding protein 4
  • Synonyms
    HsT1031
  • Links
    NCBI Gene ID: 91133
    UniProt: Q8NA19

  • Chr Location
    18p11.31; chr18:5952760-6415477 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    621
  • Tissues
    15
  • cDNA Data
    10
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041565 Ensembl Gene Model | MGI Sequence Detail 506290 C57BL/6J ±  kb
transcript ENSMUST00000124543 Ensembl | MGI Sequence Detail 4239 Not Applicable  
polypeptide ENSMUSP00000121045 Ensembl | MGI Sequence Detail 612 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    Genomic 2
    cDNA 10

    Microarray probesets 2
Other
Accession IDs
less
MGI:2443641
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory